EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr6	130956300	Silent	novel	Q62Q	0.43
BLCA	chr6	130956248	Missense_Mutation	novel	P80T	0.2
BLCA	chr6	130895069	Silent	NA	L429L	0.59
BLCA	chr6	130867526	Missense_Mutation	novel	E888A	0.36
BLCA	chr6	130901109	Missense_Mutation	novel	A334D	0.19
BLCA	chr6	130899530	Silent	NA	K399K	0.41
BLCA	chr6	130869821	Silent	rs186506443	P783P	0.16
BLCA	chr6	130870127	Splice_Site	novel	X682_splice	0.31
BLCA	chr6	130870091	Missense_Mutation	novel	K693N	0.3
BLCA	chr6	130885167	Nonsense_Mutation	novel	Q588*	0.33
BLCA	chr6	130956016	Nonsense_Mutation	novel	S157*	0.23
BRCA	chr6	130863667	Missense_Mutation	NA	T961P	0.12
BRCA	chr6	130867856	Intron	novel		0.07
BRCA	chr6	130926656	Silent	NA	L253L	0.19
BRCA	chr6	130901049	Missense_Mutation	rs778911472	G354D	0.69
BRCA	chr6	130895002	Missense_Mutation	rs765521376	R452C	0.16
BRCA	chr6	130869680	Silent	rs745805908	H830H	0.04
BRCA	chr6	130863697	Missense_Mutation	NA	E951K	0.25
BRCA	chr6	130878160	Missense_Mutation	rs140419333	R663C	0.11
BRCA	chr6	130863641	Missense_Mutation	NA	D969E	0.11
BRCA	chr6	130899569	Silent	rs150838163	S386S	0.11
BRCA	chr6	130899569	Silent	rs150838163	S386S	0.51
BRCA	chr6	130900996	Missense_Mutation	novel	E372K	0.06
BRCA	chr6	130901042	Silent	rs139333879	I356I	0.23
BRCA	chr6	130867466	Missense_Mutation	NA	S908C	0.26
CESC	chr6	130858168	Missense_Mutation	novel	E996Q	0.24
CESC	chr6	130869777	Missense_Mutation	novel	S798I	0.5
CESC	chr6	130840282	3'UTR	novel		0.31
CESC	chr6	130882814	Intron	novel		0.38
CESC	chr6	130880185	Missense_Mutation	novel	G619R	0.36
CESC	chr6	130882645	Intron	novel		0.36
CHOL	chr6	130956149	Missense_Mutation	NA	D113H	0.1
COAD	chr6	130867602	Intron	NA		0.27
COAD	chr6	130956368	Missense_Mutation	novel	D40N	0.09
COAD	chr6	130899507	Missense_Mutation	novel	D407G	0.24
COAD	chr6	130956104	Missense_Mutation	NA	D128Y	0.27
COAD	chr6	130882826	Intron	novel		0.6
COAD	chr6	130895041	Missense_Mutation	NA	R439C	0.05
COAD	chr6	130895089	Missense_Mutation	rs760954108	V423M	0.18
COAD	chr6	130955222	Missense_Mutation	NA	E196D	0.1
COAD	chr6	130901041	Missense_Mutation	rs146731749	D357N	0.31
COAD	chr6	130867771	Intron	novel		0.23
COAD	chr6	130878159	Missense_Mutation	rs201590756	R663H	0.36
COAD	chr6	130867657	Intron	novel		0.04
COAD	chr6	130878138	Missense_Mutation	rs751011583	R670Q	0.21
COAD	chr6	130890395	Missense_Mutation	NA	R520H	0.34
ESCA	chr6	130865596	Silent	novel	L923L	0.35
ESCA	chr6	130894366	Missense_Mutation	NA	V489M	0.24
ESCA	chr6	130908858	Missense_Mutation	novel	W272C	0.08
GBM	chr6	130858214	Frame_Shift_Ins	novel	*R980Sfs6**	0.11
GBM	chr6	130901156	Silent	novel	R318R	0.28
GBM	chr6	130894383	Missense_Mutation	novel	R483I	0.19
GBM	chr6	130904541	Splice_Site	novel	X285_splice	0.11
GBM	chr6	130955231	Missense_Mutation	novel	E193D	0.24
GBM	chr6	130858131	Splice_Region	novel		0.04
GBM	chr6	130869821	Silent	rs186506443	P783P	0.09
GBM	chr6	130885270	Splice_Site	novel	X554_splice	0.08
GBM	chr6	130956034	Missense_Mutation	NA	S151T	0.41
HNSC	chr6	130901124	Missense_Mutation	novel	S329C	0.14
HNSC	chr6	130870048	Missense_Mutation	novel	E708K	0.09
HNSC	chr6	130901044	Missense_Mutation	NA	I356V	0.18
HNSC	chr6	130869724	Nonsense_Mutation	novel	E816*	0.17
HNSC	chr6	130956185	Missense_Mutation	rs778628882	E101K	0.06
HNSC	chr6	130863654	Missense_Mutation	novel	D965V	0.11
HNSC	chr6	130878190	Missense_Mutation	rs374441396	R653C	0.28
HNSC	chr6	130885192	Silent	novel	P579P	0.05
HNSC	chr6	130926658	Missense_Mutation	novel	L253V	0.37
HNSC	chr6	130885151	Missense_Mutation	novel	R593K	0.13
HNSC	chr6	130956270	Missense_Mutation	novel	R72S	0.32
HNSC	chr6	130890408	Missense_Mutation	NA	R516C	0.4
KIRC	chr6	130956290	In_Frame_Del	novel	R64_E65del	0.03
KIRC	chr6	130858223	Silent	NA	R977R	0.25
KIRC	chr6	130869624	Missense_Mutation	NA	V849G	0.39
KIRC	chr6	130890419	Frame_Shift_Del	novel	*F508Vfs6**	0.16
KIRP	chr6	130895079	Missense_Mutation	novel	N426S	0.43
LAML	chr6	130867692	Intron	novel		0.21
LAML	chr6	130904497	Silent	novel	P299P	0.26
LGG	chr6	130908833	Frame_Shift_Del	novel	*K280Dfs3**	0.35
LIHC	chr6	130895011	Missense_Mutation	novel	S449A	0.2
LIHC	chr6	130858173	Missense_Mutation	NA	H994R	0.38
LUAD	chr6	130894368	Missense_Mutation	novel	C488F	0.24
LUAD	chr6	130869614	Missense_Mutation	novel	E852D	0.17
LUAD	chr6	130880191	Missense_Mutation	novel	V617L	0.12
LUAD	chr6	130956140	Missense_Mutation	novel	E116K	0.27
LUAD	chr6	130895089	Missense_Mutation	NA	V423L	0.12
LUAD	chr6	130867510	Missense_Mutation	novel	E893D	0.14
LUAD	chr6	130869759	Missense_Mutation	novel	G804V	0.19
LUAD	chr6	130956413	Missense_Mutation	NA	E25K	0.08
LUAD	chr6	130865618	Missense_Mutation	novel	G916V	0.11
LUAD	chr6	130869656	Missense_Mutation	novel	M838I	0.26
LUAD	chr6	130869657	Missense_Mutation	novel	M838K	0.26
LUAD	chr6	130890333	Missense_Mutation	rs751876828	R541C	0.14
LUAD	chr6	130885183	Silent	novel	V582V	0.12
LUAD	chr6	130869673	Missense_Mutation	rs150873575	A833S	0.32
LUAD	chr6	130956163	Missense_Mutation	NA	E108G	0.32
LUAD	chr6	130878124	Silent	novel	L675L	0.13
LUAD	chr6	130956125	Nonsense_Mutation	novel	E121*	0.59
LUAD	chr6	130869998	Silent	rs778645504	R724R	0.16
LUAD	chr6	130926613	Nonsense_Mutation	NA	E268*	0.14
LUAD	chr6	130956094	Missense_Mutation	novel	E131V	0.07
LUSC	chr6	130900963	Missense_Mutation	novel	R383W	0.16
LUSC	chr6	130901049	Missense_Mutation	novel	G354V	0.15
LUSC	chr6	130900982	Silent	NA	A376A	0.68
LUSC	chr6	130878140	Silent	novel	K669K	0.39
LUSC	chr6	130955218	Nonsense_Mutation	NA	Q198*	0.13
LUSC	chr6	130869834	Missense_Mutation	novel	E779V	0.11
LUSC	chr6	130894379	Silent	rs758585681	L484L	0.26
LUSC	chr6	130894973	Silent	rs531092647	P461P	0.22
LUSC	chr6	130904499	Missense_Mutation	NA	P299T	0.56
LUSC	chr6	130865590	Silent	NA	A925A	0.34
LUSC	chr6	130880182	Missense_Mutation	novel	D620H	0.1
LUSC	chr6	130955171	Missense_Mutation	novel	K213N	0.27
LUSC	chr6	130956146	Missense_Mutation	novel	K114Q	0.33
LUSC	chr6	130870026	Missense_Mutation	NA	S715L	0.16
LUSC	chr6	130870009	Missense_Mutation	novel	G721R	0.1
OV	chr6	130867862	Intron	novel		0.18
OV	chr6	130901157	Missense_Mutation	NA	R318P	0.28
PAAD	chr6	130878200	Silent	novel	S649S	0.18
PAAD	chr6	130955318	Splice_Site	novel	X165_splice	0.16
PRAD	chr6	130870086	Missense_Mutation	rs753274531	R695Q	0.18
PRAD	chr6	130956259	Missense_Mutation	rs774621932	R76Q	0.09
PRAD	chr6	130895027	Silent	rs376962561	P443P	0.27
PRAD	chr6	130863664	Missense_Mutation	NA	G962R	0.26
PRAD	chr6	130867668	Intron	novel		0.38
PRAD	chr6	130901136	Missense_Mutation	rs375486728	R325H	0.39
READ	chr6	130901181	Splice_Site	novel	X310_splice	0.36
READ	chr6	130956379	Missense_Mutation	NA	N36S	0.3
SARC	chr6	130880673	Intron	novel		0.3
SARC	chr6	130867844	Intron	novel		0.4
SARC	chr6	130900959	Splice_Region	novel		0.46
SKCM	chr6	130867520	Missense_Mutation	NA	S890F	0.19
SKCM	chr6	130869822	Missense_Mutation	rs547603639	P783L	0.44
SKCM	chr6	130956311	Missense_Mutation	NA	L59V	0.32
SKCM	chr6	130904473	Missense_Mutation	NA	D307E	0.34
SKCM	chr6	130869850	Missense_Mutation	novel	E774K	0.48
SKCM	chr6	130869963	Missense_Mutation	rs755692646	S736F	0.41
SKCM	chr6	130865570	Missense_Mutation	rs759667681	S932F	0.42
SKCM	chr6	130878120	Missense_Mutation	NA	S676F	0.89
SKCM	chr6	130878120	Missense_Mutation	NA	S676F	0.87
SKCM	chr6	130908834	Silent	novel	K280K	0.51
SKCM	chr6	130956346	Missense_Mutation	novel	S47F	0.1
SKCM	chr6	130870091	Silent	NA	K693K	0.44
SKCM	chr6	130899530	Silent	NA	K399K	0.36
SKCM	chr6	130908844	Missense_Mutation	novel	K277I	0.16
SKCM	chr6	130926637	Missense_Mutation	NA	G260R	0.2
SKCM	chr6	130956287	Missense_Mutation	NA	E67K	0.46
SKCM	chr6	130895041	Missense_Mutation	NA	R439C	0.3
SKCM	chr6	130867658	Intron	novel		0.23
SKCM	chr6	130885100	Missense_Mutation	NA	G610E	0.55
SKCM	chr6	130900967	Silent	novel	T381T	0.11
SKCM	chr6	130955214	Missense_Mutation	NA	T199I	0.29
SKCM	chr6	130870026	Missense_Mutation	NA	S715L	0.21
SKCM	chr6	130899570	Missense_Mutation	NA	S386L	1
SKCM	chr6	130878179	Missense_Mutation	NA	M656I	0.16
SKCM	chr6	130956053	Missense_Mutation	NA	E145K	0.18
SKCM	chr6	130895077	Missense_Mutation	NA	G427R	0.15
SKCM	chr6	130869828	Missense_Mutation	NA	P781L	0.88
SKCM	chr6	130895041	Missense_Mutation	NA	R439C	0.46
SKCM	chr6	130901091	Missense_Mutation	NA	T340S	0.18
SKCM	chr6	130869652	Missense_Mutation	novel	E840K	0.55
SKCM	chr6	130869954	Missense_Mutation	novel	S739F	0.67
SKCM	chr6	130901041	Missense_Mutation	rs146731749	D357N	0.09
SKCM	chr6	130890408	Missense_Mutation	NA	R516C	0.16
SKCM	chr6	130904501	Missense_Mutation	novel	P298L	0.3
SKCM	chr6	130956335	Missense_Mutation	NA	P51S	0.38
STAD	chr6	130904488	Silent	NA	S302S	0.3
STAD	chr6	130901136	Missense_Mutation	rs375486728	R325H	0.13
STAD	chr6	130858193	Silent	rs761915215	S987S	0.04
STAD	chr6	130885193	Missense_Mutation	NA	P579H	0.37
STAD	chr6	130955276	Missense_Mutation	NA	K178N	0.37
STAD	chr6	130955997	Missense_Mutation	novel	M163I	0.38
STAD	chr6	130956291	Silent	NA	E65E	0.07
STAD	chr6	130869999	Missense_Mutation	rs150621192	R724H	0.44
STAD	chr6	130870092	Missense_Mutation	NA	K693M	0.12
STAD	chr6	130878160	Missense_Mutation	rs140419333	R663C	0.19
STAD	chr6	130885213	Silent	NA	G572G	0.2
STAD	chr6	130885157	Missense_Mutation	rs765506413	D591G	0.07
STAD	chr6	130926610	Nonsense_Mutation	novel	Q269*	0.12
STAD	chr6	130869717	Missense_Mutation	NA	V818A	0.29
STAD	chr6	130956185	Frame_Shift_Ins	novel	*E101Rfs8**	0.11
THCA	chr6	130867627	Intron	novel		0.09
UCEC	chr6	130882639	Intron	novel		0.15
UCEC	chr6	130955276	Silent	NA	K178K	0.34
UCEC	chr6	130895049	Missense_Mutation	NA	R436Q	0.3
UCEC	chr6	130890332	Missense_Mutation	rs764887205	R541H	0.39
UCEC	chr6	130869638	Silent	novel	E844E	0.04
UCEC	chr6	130867636	Intron	novel		0.41
UCEC	chr6	130869594	Missense_Mutation	novel	D859G	0.32
UCEC	chr6	130869814	Missense_Mutation	novel	K786Q	0.37
UCEC	chr6	130885096	Splice_Region	novel	K611K	0.31
UCEC	chr6	130867646	Intron	novel		0.05
UCEC	chr6	130867647	Intron	novel		0.05
UCEC	chr6	130890342	Missense_Mutation	novel	H538Y	0.4
UCEC	chr6	130869852	Missense_Mutation	NA	Y773C	0.16
UCEC	chr6	130908849	Silent	NA	P275P	0.13
UCEC	chr6	130926698	Missense_Mutation	novel	K239N	0.1
UCEC	chr6	130956107	Missense_Mutation	NA	G127C	0.27
UCEC	chr6	130878189	Missense_Mutation	rs370238340	R653H	0.33
UCEC	chr6	130869922	Missense_Mutation	NA	E750K	0.29
UCEC	chr6	130900979	Missense_Mutation	novel	E377D	0.09
UCEC	chr6	130955124	Missense_Mutation	novel	E229G	0.14
UCEC	chr6	130885234	Silent	novel	K565K	0.06
UCEC	chr6	130955231	Missense_Mutation	novel	E193D	0.07
UCEC	chr6	130895049	Missense_Mutation	NA	R436Q	0.12
UCEC	chr6	130901031	Missense_Mutation	novel	E360A	0.32
UCEC	chr6	130908842	Nonsense_Mutation	novel	E278*	0.14
UCEC	chr6	130867573	Silent	novel	V872V	0.05
UCEC	chr6	130869962	Silent	novel	S736S	0.25
UCEC	chr6	130878167	Silent	novel	P660P	0.24
UCEC	chr6	130956278	Missense_Mutation	novel	E70K	0.24
UCEC	chr6	130882985	Intron	novel		0.11
UCEC	chr6	130956043	Missense_Mutation	NA	P148H	0.32
UCEC	chr6	130880862	Intron	novel		0.1
UCEC	chr6	130867563	Nonsense_Mutation	novel	E876*	0.15
UCEC	chr6	130956161	Nonsense_Mutation	novel	E109*	0.13
UCEC	chr6	130882991	Intron	novel		0.43
UCEC	chr6	130869913	Missense_Mutation	rs748999213	V753M	0.27
UCEC	chr6	130956117	Missense_Mutation	novel	R123S	0.63
UCEC	chr6	130956407	Missense_Mutation	rs368404556	P27S	0.48
UCEC	chr6	130876740	Intron	novel		0.4
UCEC	chr6	130858243	Missense_Mutation	NA	A971S	0.42
UCEC	chr6	130956072	Missense_Mutation	NA	E138D	0.36
UCEC	chr6	130890352	Silent	novel	R534R	0.29
UCEC	chr6	130870048	Nonsense_Mutation	NA	E708*	0.07
UCEC	chr6	130956249	Silent	rs373413431	P79P	0.35
UCEC	chr6	130883000	Intron	novel		0.44
UCEC	chr6	130956322	Missense_Mutation	novel	S55I	0.4
UCEC	chr6	130955290	Nonsense_Mutation	novel	E174*	0.12
UCEC	chr6	130895027	Silent	rs376962561	P443P	0.21
UCEC	chr6	130956095	Nonsense_Mutation	novel	E131*	0.14
UCEC	chr6	130840230	3'UTR	novel		0.38
UCEC	chr6	130880144	Missense_Mutation	novel	E632D	0.25
UCEC	chr6	130882545	Intron	novel		0.19
UCEC	chr6	130926636	Missense_Mutation	novel	G260E	0.19
UCEC	chr6	130956197	Nonsense_Mutation	novel	G97*	0.1
UCEC	chr6	130956500	Splice_Site	novel		0.33
UCEC	chr6	130869680	Silent	rs745805908	H830H	0.09
UCEC	chr6	130956186	Frame_Shift_Del	novel	*E101Sfs12**	0.06
UCEC	chr6	130908835	Frame_Shift_Del	NA	*K280Efs13**	0.37
UCEC	chr6	130869850	Missense_Mutation	novel	E774K	0.47
UCEC	chr6	130956107	Missense_Mutation	novel	G127S	0.26
UCEC	chr6	130885117	Silent	novel	H604H	0.1
UCEC	chr6	130869927	Missense_Mutation	novel	S748N	0.47
UCEC	chr6	130870068	Missense_Mutation	novel	D701V	0.41
UCEC	chr6	130956124	Frame_Shift_Ins	novel	*E121Gfs7**	0.07
UCEC	chr6	130956034	Missense_Mutation	novel	S151N	0.36
UCEC	chr6	130867551	Missense_Mutation	novel	I880L	0.08
UCEC	chr6	130895049	Missense_Mutation	NA	R436Q	0.22
UCEC	chr6	130865598	Frame_Shift_Ins	novel	*L923Sfs16**	0.04
UCEC	chr6	130869652	Nonsense_Mutation	novel	E840*	0.27
UCEC	chr6	130870067	Silent	rs117884190	D701D	0.24
UCEC	chr6	130878161	Silent	rs376910072	P662P	0.09
UCEC	chr6	130901112	Missense_Mutation	rs757603022	H333R	0.25
UCEC	chr6	130956307	Missense_Mutation	rs370441861	R60H	0.29
UCEC	chr6	130956413	Nonsense_Mutation	novel	E25*	0.3
UCEC	chr6	130882615	Intron	novel		0.41
UCEC	chr6	130899569	Silent	rs150838163	S386S	0.25
UCEC	chr6	130955125	Missense_Mutation	rs375264771	E229K	0.33
UCEC	chr6	130869747	Frame_Shift_Del	novel	*V807Afs3**	0.24
UCEC	chr6	130878225	Missense_Mutation	novel	I641T	0.49
UCEC	chr6	130869881	Silent	NA	T763T	0.39
UCEC	chr6	130876721	Intron	novel		0.52
UCEC	chr6	130858237	Missense_Mutation	novel	A973S	0.06
UCEC	chr6	130869989	Missense_Mutation	novel	E727D	0.44
UCS	chr6	130878190	Missense_Mutation	rs374441396	R653C	0.41
UCS	chr6	130867613	Intron	novel		0.42
UCS	chr6	130880207	Splice_Site	novel	X612_splice	0.44
UCS	chr6	130858150	Missense_Mutation	novel	E1002Q	0.12

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	DEL	0.25	0.00052595
GBM	DEL	0.2357	1.056e-05
KIRC	DEL	0.2405	7.439e-11
LGG	DEL	0.1404	0.0054594
MESO	DEL	0.4138	0.05642
PAAD	DEL	0.3587	0.11274
SKCM	DEL	0.5368	1.5442e-06
THYM	DEL	0.1301	0.10691

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0045	Kaplan-Meier Survival Analysis
STAD	0.0022	Kaplan-Meier Survival Analysis
MESO	0.019	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
COAD	0.019	Kaplan-Meier Survival Analysis
BLCA	0.043	Kaplan-Meier Survival Analysis
READ	0.00056	Kaplan-Meier Survival Analysis
LAML	0.0038	Kaplan-Meier Survival Analysis
KICH	0.0091	Kaplan-Meier Survival Analysis
UCEC	0.0035	Kaplan-Meier Survival Analysis
LIHC	0.0016	Kaplan-Meier Survival Analysis
LGG	0.037	Kaplan-Meier Survival Analysis
OV	0.00013	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000079819 (Gene tree)
Gene ID: 2037
Gene Symbol: EPB41L2
Alias: 4.1-G
Full Name: erythrocyte membrane protein band 4.1 like 2
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 235,150 bases
Position: chr6:130,828,173-131,063,322
Accession: 3379
Summary: (Erythrocyte Membrane Protein Band 4.1 Like 2) is a Protein Coding gene. Diseases associated with EPB41L2 include Suppression Of Tumorigenicity 12. Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. Gene Ontology (GO) annotations related to this gene include actin binding and cytoskeletal protein binding. An important paralog of this gene is EPB41L3.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000531410	EPB41L2-228	2926	-	ENSP00000434596	126 (aa)	-	E9PPC9
ENST00000530707	EPB41L2-225	565	-	ENSP00000435556	118 (aa)	-	E9PJP4
ENST00000526782	EPB41L2-213	424	-	-	- (aa)	-	-
ENST00000445890	EPB41L2-205	3677	-	ENSP00000402041	747 (aa)	-	O43491
ENST00000456097	EPB41L2-207	1138	-	ENSP00000397580	380 (aa)	-	H0Y5B0
ENST00000529709	EPB41L2-222	585	-	ENSP00000436871	179 (aa)	-	E9PQD2
ENST00000628542	EPB41L2-232	4247	-	ENSP00000486691	935 (aa)	-	E9PHY5
ENST00000639623	EPB41L2-233	3395	-	ENSP00000494672	824 (aa)	-	A0A2R8Y5B3
ENST00000392427	EPB41L2-204	3369	-	ENSP00000376222	673 (aa)	-	O43491
ENST00000527423	EPB41L2-217	962	-	ENSP00000437295	268 (aa)	-	E9PMV8
ENST00000524581	EPB41L2-208	3090	-	ENSP00000437207	383 (aa)	-	Q6R5J7
ENST00000527017	EPB41L2-215	727	-	ENSP00000432949	240 (aa)	-	E9PN54
ENST00000534166	EPB41L2-231	572	-	-	- (aa)	-	-
ENST00000525271	EPB41L2-211	2568	-	ENSP00000432803	673 (aa)	-	O43491
ENST00000528282	EPB41L2-220	3663	-	ENSP00000434308	747 (aa)	-	O43491
ENST00000337057	EPB41L2-201	4457	XM_011535524	ENSP00000338481	1005 (aa)	XP_011533826	O43491
ENST00000530148	EPB41L2-223	664	-	-	- (aa)	-	-
ENST00000368126	EPB41L2-202	715	-	-	- (aa)	-	-
ENST00000525198	EPB41L2-210	981	-	ENSP00000434998	224 (aa)	-	E9PMG5
ENST00000530757	EPB41L2-226	4360	-	ENSP00000436349	201 (aa)	-	Q6ZSX4
ENST00000368128	EPB41L2-203	4456	XM_017010350	ENSP00000357110	1005 (aa)	XP_016865839	O43491
ENST00000525193	EPB41L2-209	2121	-	ENSP00000431988	706 (aa)	-	E9PII3
ENST00000530481	EPB41L2-224	3914	-	ENSP00000434576	852 (aa)	-	O43491
ENST00000531356	EPB41L2-227	588	-	ENSP00000436145	127 (aa)	-	E9PQN0
ENST00000452150	EPB41L2-206	2994	-	-	- (aa)	-	-
ENST00000533912	EPB41L2-230	514	-	-	- (aa)	-	-
ENST00000528179	EPB41L2-219	560	-	-	- (aa)	-	-
ENST00000527659	EPB41L2-218	2436	-	ENSP00000431647	811 (aa)	-	E9PK52
ENST00000526333	EPB41L2-212	549	-	-	- (aa)	-	-
ENST00000529208	EPB41L2-221	3023	-	ENSP00000436641	935 (aa)	-	E9PHY5
ENST00000526983	EPB41L2-214	552	-	ENSP00000432329	153 (aa)	-	E9PRG1
ENST00000527411	EPB41L2-216	4186	XM_011535528	ENSP00000436348	935 (aa)	XP_011533830	E9PHY5
ENST00000532499	EPB41L2-229	591	-	ENSP00000432013	162 (aa)	-	E9PIG0

Gene Model

Click here to download ENSG00000079819's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000079819	Cholesterol, HDL	3.2518174920345E-7	17903299
ENSG00000079819	Cholesterol, HDL	2.17227992254415E-6	17903299
ENSG00000079819	Cholesterol, HDL	5.94508334821237E-7	17903299
ENSG00000079819	Cholesterol, HDL	1.79466764483281E-7	17903299
ENSG00000079819	CD40 Ligand	7.92033313053052E-8	17903293
ENSG00000079819	Electrocardiography	1.37426494733452E-12	17903302
ENSG00000079819	Electrocardiography	2.02853586778398E-9	17903302
ENSG00000079819	Electrocardiography	3.30431018060061E-8	17903302
ENSG00000079819	Electrocardiography	5.25565872108497E-8	17903302
ENSG00000079819	Hematocrit	4.1170000E-005	-
ENSG00000079819	Platelet Function Tests	1.9400000E-006	-
ENSG00000079819	Platelet Function Tests	1.7200000E-006	-
ENSG00000079819	Hydroxymethylglutaryl CoA Reductases	2E-7	22331829
ENSG00000079819	Cholesterol, LDL	2E-7	22331829
ENSG00000079819	Corpus Striatum	5E-6	22903471
ENSG00000079819	Immunoglobulins	2E-6	23382691

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000079819	rs6921542	6	131006940	C	Mean corpuscular volume	27863252	[0.018-0.034] unit decrease	0.02573725	EFO_0004526
ENSG00000079819	rs6908917	6	131034724	C	IgG glycosylation	23382691	[0.098-0.236] unit increase	0.1674	EFO_0005193
ENSG00000079819	rs6941712	6	130961070	C	Lentiform nucleus volume	22903471	[NR] unit decrease	149.67	EFO_0004913
ENSG00000079819	rs5880046	6	131005179	GT	Heel bone mineral density	28869591	[0.012-0.033] unit increase	0.0223833	EFO_0009270
ENSG00000079819	rs5880046	6	131005179	GT	Heel bone mineral density	28869591	[0.021-0.034] unit increase	0.027655	EFO_0009270
ENSG00000079819	rs5880046	6	131005179	GT	Heel bone mineral density	28869591	[0.021-0.04] unit increase	0.0301183	EFO_0009270
ENSG00000079819	rs7769153	6	130935224	?	Response to statins (LDL cholesterol change)	22331829	[6.77-13.83] % increase	10.3	GO_0036273\|EFO_0007804
ENSG00000079819	rs5880046	6	131005179	?	Heel bone mineral density	30048462	[0.023-0.032] unit increase	0.0274138	EFO_0009270
ENSG00000079819	rs4895901	6	130986042	?	Heel bone mineral density	30048462	[0.023-0.032] unit increase	0.0275732	EFO_0009270
ENSG00000079819	rs9492774	6	130981349	C	Educational attainment (years of education)	30038396	[0.0051-0.0109] unit increase	0.008	EFO_0004784
ENSG00000079819	rs1571911	6	130872806	C	Heel bone mineral density	30598549	[0.011-0.02] unit decrease	0.0152984	EFO_0009270
ENSG00000079819	rs4895901	6	130986042	T	Heel bone mineral density	30598549	[0.027-0.035] unit increase	0.0309682	EFO_0009270
ENSG00000079819	rs6903705	6	131058527	?	Balding type 1	30595370			EFO_0007825
ENSG00000079819	rs6903705	6	131058527	T	Male-pattern baldness	30573740	[0.03-0.044] unit increase	0.0368459	EFO_0007825
ENSG00000079819	rs7770860	6	130865253	T	Loneliness	29970889	[0.0031-0.0063] unit decrease	0.0047	EFO_0007865
ENSG00000079819	rs7770860	6	130865253	T	Loneliness (MTAG)	29970889	[0.0087-0.0171] unit decrease	0.012899768	EFO_0007865
ENSG00000079819	rs9885632	6	130990769	T	Systolic blood pressure	30224653	[0.16-0.26] mmHg increase	0.2102	EFO_0006335
ENSG00000079819	rs9885632	6	130990769	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000079819	rs872576	6	130846909	?	Neuroticism	30595370			EFO_0007660
ENSG00000079819	rs12203760	6	131028477	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000079819	rs13437326	6	131050995	?	Heel bone mineral density	30595370			EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000079819's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000079819	EPB41L2	99	94.118	ENSMUSG00000019978	Epb41l2	98	92.708	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003779	actin binding	-	IEA	Function
GO:0005198	structural molecule activity	-	IEA	Function
GO:0005515	protein binding	23870127.24996901.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0005886	plasma membrane	-	IDA	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0007049	cell cycle	-	IEA	Process
GO:0008091	spectrin	9598318.	TAS	Component
GO:0008180	COP9 signalosome	18850735.	IDA	Component
GO:0030054	cell junction	-	IDA	Component
GO:0030507	spectrin binding	-	IEA	Function
GO:0030866	cortical actin cytoskeleton organization	-	IEA	Process
GO:0031032	actomyosin structure organization	21873635.	IBA	Process
GO:0042731	PH domain binding	-	IEA	Function
GO:0051301	cell division	-	IEA	Process
GO:0070062	extracellular exosome	20458337.	HDA	Component
GO:0099738	cell cortex region	23870127.	IDA	Component
GO:1904778	positive regulation of protein localization to cell cortex	23870127.	IMP	Process

EuRBPDB

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Description

RBPome

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

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