EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25337201	Overexpression of Rsf-1 correlates with pathological type, p53 status and survival in primary breast cancer.	Int J Clin Exp Pathol	2014 Aug 15	Ren J	-
20228782	Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase.	Mod Pathol	2010 Jun	Sehdev AS	doi: 10.1038/modpathol.2010.60
23456648	Quantification of serum HBXAP DNA in lung cancer patients by quantitative fluorescent polymerase chain reaction.	Mol Biol Rep	2013 Jun	Hou YL	doi: 10.1007/s11033-013-2488-4
22528946	Rsf-1 overexpression correlates with poor prognosis and cell proliferation in colon cancer.	Tumour Biol	2012 Oct	Liu S	doi: 10.1007/s13277-012-0399-y
24584698	Rsf-1 overexpression in human prostate cancer, implication as a prognostic marker.	Tumour Biol	2014 Jun	Li H	doi: 10.1007/s13277-014-1766-7
18314909	Amplification of 11q13 in ovarian carcinoma.	Genes Chromosomes Cancer	2008 Jun	Brown LA	doi: 10.1002/gcc.20549.
22569540	Rsf-1 expression in rectal cancer: with special emphasis on the independent prognostic value after neoadjuvant chemoradiation.	J Clin Pathol	2012 Aug	Lin CY	doi: 10.1136/jclinpath-2012-200786
16172393	Amplification of a chromatin remodeling gene, Rsf-1/HBXAP, in ovarian carcinoma.	Proc Natl Acad Sci U S A	2005 Sep 27	Shih IeM	-
16418735	Identification of remodeling and spacing factor 1 (rsf-1, HBXAP) at chromosome 11q13 as a putative oncogene in ovarian cancer.	Eur J Hum Genet	2006 Apr	Hennessy BT	-
28289901	Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.	Virchows Arch	2017 May	Zhang X	doi: 10.1007/s00428-017-2102-6
29048677	MicroRNA-154 as a prognostic factor in bladder cancer inhibits cellular malignancy by targeting RSF1 and RUNX2.	Oncol Rep	2017 Nov	Zhao X	doi: 10.3892/or.2017.5992

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr11	77701554	Missense_Mutation	novel	T559A	0.41
BLCA	chr11	77675149	Missense_Mutation	novel	R1150Q	0.26
BLCA	chr11	77667078	Missense_Mutation	novel	E1389K	0.28
BLCA	chr11	77701668	Missense_Mutation	novel	E521Q	0.29
BLCA	chr11	77675180	Missense_Mutation	novel	D1140N	0.42
BLCA	chr11	77675103	Missense_Mutation	novel	K1165N	0.07
BLCA	chr11	77701813	Silent	novel	Y472Y	0.06
BLCA	chr11	77667094	Missense_Mutation	rs776494197	L1383F	0.43
BLCA	chr11	77701821	Missense_Mutation	novel	E470Q	0.1
BLCA	chr11	77702190	Missense_Mutation	NA	E347K	0.16
BLCA	chr11	77667213	Missense_Mutation	novel	E1344Q	0.13
BLCA	chr11	77701473	Missense_Mutation	novel	E586Q	0.08
BLCA	chr11	77700969	Missense_Mutation	novel	E754Q	0.18
BLCA	chr11	77700852	Missense_Mutation	NA	D793N	0.35
BLCA	chr11	77701805	Missense_Mutation	novel	S475F	0.44
BLCA	chr11	77698581	Missense_Mutation	NA	S874L	0.36
BLCA	chr11	77666993	Missense_Mutation	NA	A1417G	0.13
BLCA	chr11	77702208	Missense_Mutation	novel	E341K	0.22
BRCA	chr11	77701155	Missense_Mutation	novel	E692Q	0.03
BRCA	chr11	77701240	Missense_Mutation	NA	K663N	0.2
BRCA	chr11	77667296	Missense_Mutation	NA	G1316A	0.29
BRCA	chr11	77747074	Missense_Mutation	novel	L112I	0.09
BRCA	chr11	77685155	Missense_Mutation	novel	E969Q	0.07
BRCA	chr11	77693552	Silent	NA	L925L	0.28
BRCA	chr11	77701653	Frame_Shift_Ins	novel	*K526Sfs18**	0.05
BRCA	chr11	77701584	Missense_Mutation	NA	D549Y	0.05
CESC	chr11	77764555	Intron	novel		0.32
CESC	chr11	77747119	Missense_Mutation	NA	E97Q	0.16
CESC	chr11	77701800	Missense_Mutation	NA	D477N	0.3
CESC	chr11	77666954	Missense_Mutation	novel	D1430G	0.07
CESC	chr11	77725700	Splice_Site	NA	X193_splice	0.16
CESC	chr11	77701046	Missense_Mutation	novel	R728M	0.33
CESC	chr11	77701762	Silent	NA	S489S	0.13
CESC	chr11	77667443	Nonsense_Mutation	NA	S1267*	0.82
COAD	chr11	77698653	Nonsense_Mutation	novel	W845_T850delins*	0.28
COAD	chr11	77698572	Missense_Mutation	novel	E877V	0.27
COAD	chr11	77675150	Nonsense_Mutation	NA	R1150*	0.36
COAD	chr11	77764610	Frame_Shift_Del	NA	*K89Nfs3**	0.28
COAD	chr11	77701469	Missense_Mutation	novel	K587R	0.1
COAD	chr11	77698672	Nonsense_Mutation	NA	R844*	0.22
COAD	chr11	77672102	Nonsense_Mutation	NA	R1231*	0.21
COAD	chr11	77701728	Missense_Mutation	novel	E501K	0.45
COAD	chr11	77691232	Missense_Mutation	NA	L943F	0.27
COAD	chr11	77667429	Nonsense_Mutation	NA	R1272*	0.06
COAD	chr11	77672102	Nonsense_Mutation	NA	R1231*	0.27
COAD	chr11	77701239	Frame_Shift_Ins	NA	*V664Sfs11**	0.19
COAD	chr11	77701568	Missense_Mutation	novel	T554S	0.05
COAD	chr11	77701570	Silent	novel	K553K	0.04
COAD	chr11	77676958	Missense_Mutation	novel	R1059C	0.36
COAD	chr11	77676883	Nonsense_Mutation	novel	R1084*	0.19
COAD	chr11	77700805	Missense_Mutation	novel	E808D	0.35
COAD	chr11	77675200	Missense_Mutation	rs200271333	P1133L	0.54
COAD	chr11	77701030	Silent	NA	I733I	0.08
COAD	chr11	77666793	3'UTR	novel		0.3
COAD	chr11	77683787	Missense_Mutation	NA	K996N	0.37
COAD	chr11	77725675	Silent	NA	T201T	0.4
COAD	chr11	77672169	Silent	NA	R1208R	0.28
COAD	chr11	77701789	Silent	novel	I480I	0.05
COAD	chr11	77701225	Silent	NA	T668T	0.36
COAD	chr11	77702176	Silent	rs756106440	I351I	0.27
COAD	chr11	77701705	Frame_Shift_Ins	novel	*L509Vfs8**	0.05
ESCA	chr11	77672109	Silent	novel	K1228K	0.54
GBM	chr11	77666823	3'UTR	novel		0.39
GBM	chr11	77672099	Missense_Mutation	rs779136727	R1232C	0.46
GBM	chr11	77701754	Missense_Mutation	novel	S492F	0.2
GBM	chr11	77672154	Silent	novel	R1213R	0.06
GBM	chr11	77702423	Missense_Mutation	rs755144281	N269S	0.48
HNSC	chr11	77702089	Silent	novel	A380A	0.44
HNSC	chr11	77683769	Frame_Shift_Del	novel	*K1002Nfs18**	0.29
HNSC	chr11	77740876	Missense_Mutation	novel	D145N	0.22
HNSC	chr11	77701046	Missense_Mutation	novel	R728M	0.13
HNSC	chr11	77701915	Silent	novel	G438G	0.32
HNSC	chr11	77667475	Silent	novel	K1256K	0.07
HNSC	chr11	77675199	Silent	novel	P1133P	0.5
HNSC	chr11	77691166	Nonsense_Mutation	novel	E965*	0.24
HNSC	chr11	77702535	Intron	novel		0.23
HNSC	chr11	77701327	Missense_Mutation	novel	I634M	0.07
HNSC	chr11	77666938	Silent	novel	V1435V	0.21
HNSC	chr11	77667248	Nonsense_Mutation	novel	S1332*	0.29
HNSC	chr11	77701432	Silent	rs762997932	D599D	0.22
KIRC	chr11	77667259	Silent	NA	R1328R	0.17
KIRC	chr11	77701615	Missense_Mutation	NA	E538D	0.18
KIRC	chr11	77701315	Nonsense_Mutation	NA	C638*	0.32
KIRC	chr11	77764436	Intron	novel		0.08
KIRP	chr11	77701163	Missense_Mutation	novel	S689Y	0.4
KIRP	chr11	77666864	3'UTR	rs577979433		0.4
KIRP	chr11	77667008	Frame_Shift_Ins	novel	*G1412Vfs16**	0.32
LAML	chr11	77701266	Missense_Mutation	novel	T655P	0.05
LAML	chr11	77676788	Splice_Site	novel	X1109_splice	0.2
LAML	chr11	77666940	Missense_Mutation	novel	V1435I	0.04
LGG	chr11	77675251	Missense_Mutation	NA	Q1116R	0.49
LGG	chr11	77702448	Missense_Mutation	novel	D261N	0.32
LGG	chr11	77672045	Nonsense_Mutation	novel	E1250*	0.41
LGG	chr11	77676910	Missense_Mutation	NA	K1075E	0.05
LGG	chr11	77701118	Frame_Shift_Ins	novel	*S704Kfs6**	0.45
LGG	chr11	77701612	Silent	novel	T539T	0.32
LIHC	chr11	77700831	Frame_Shift_Del	NA	*R800Efs24**	0.41
LIHC	chr11	77701466	Missense_Mutation	novel	L588S	0.37
LIHC	chr11	77702451	Missense_Mutation	novel	M260V	0.29
LIHC	chr11	77698537	Missense_Mutation	novel	D889Y	0.4
LIHC	chr11	77698615	Missense_Mutation	novel	E863K	0.17
LIHC	chr11	77764564	Intron	novel		0.29
LUAD	chr11	77725604	Missense_Mutation	novel	R225L	0.19
LUAD	chr11	77667417	Nonsense_Mutation	NA	R1276*	0.05
LUAD	chr11	77667055	Missense_Mutation	novel	D1396E	0.09
LUAD	chr11	77672179	Missense_Mutation	novel	R1205K	0.27
LUAD	chr11	77701042	Silent	novel	Q729Q	0.4
LUAD	chr11	77691159	Missense_Mutation	novel	R967I	0.56
LUAD	chr11	77700977	Missense_Mutation	NA	K751I	0.25
LUAD	chr11	77700721	Missense_Mutation	novel	K836N	0.27
LUAD	chr11	77676990	Missense_Mutation	rs763953559	R1048Q	0.05
LUAD	chr11	77678119	Missense_Mutation	novel	I1034V	0.08
LUAD	chr11	77667092	Missense_Mutation	novel	I1384S	0.24
LUAD	chr11	77700931	Silent	rs113637838	E766E	0.3
LUAD	chr11	77702190	Nonsense_Mutation	NA	E347*	0.33
LUAD	chr11	77666881	3'UTR	novel		0.08
LUSC	chr11	77702562	Intron	novel		0.38
LUSC	chr11	77678131	Missense_Mutation	novel	I1030V	0.13
LUSC	chr11	77702071	Frame_Shift_Del	NA	*K386Nfs6**	0.22
LUSC	chr11	77702497	Splice_Site	novel	X245_splice	0.03
LUSC	chr11	77675173	Missense_Mutation	NA	D1142G	0.46
LUSC	chr11	77701695	Missense_Mutation	novel	D512Y	0.37
LUSC	chr11	77701237	Silent	NA	V664V	0.17
LUSC	chr11	77676926	Silent	novel	E1069E	0.15
LUSC	chr11	77701408	Silent	NA	P607P	0.42
LUSC	chr11	77683787	Silent	novel	K996K	0.3
LUSC	chr11	77693514	Missense_Mutation	NA	C938F	0.48
LUSC	chr11	77701535	Missense_Mutation	novel	K565I	0.08
LUSC	chr11	77701446	Missense_Mutation	NA	F595L	0.2
LUSC	chr11	77764540	Intron	novel		0.15
LUSC	chr11	77672089	Missense_Mutation	novel	E1235A	0.2
LUSC	chr11	77700720	Splice_Site	novel	X836_splice	0.14
OV	chr11	77702682	Intron	novel		0.17
OV	chr11	77764436	Intron	novel		0.06
OV	chr11	77764436	Intron	novel		0.1
OV	chr11	77667143	Missense_Mutation	NA	D1367G	0.31
OV	chr11	77764436	Intron	novel		0.2
OV	chr11	77740931	Silent	NA	L126L	0.23
OV	chr11	77701222	Silent	novel	L669L	0.37
OV	chr11	77764436	Intron	novel		0.09
PAAD	chr11	77701651	Frame_Shift_Del	novel	*A527Hfs3**	0.06
PCPG	chr11	77675250	Silent	rs779713699	Q1116Q	0.67
PRAD	chr11	77701407	Missense_Mutation	novel	E608Q	0.34
PRAD	chr11	77701294	Missense_Mutation	novel	K645N	0.1
READ	chr11	77698672	Nonsense_Mutation	NA	R844*	0.29
READ	chr11	77700973	Silent	novel	V752V	0.21
READ	chr11	77764615	Missense_Mutation	NA	E88K	0.28
READ	chr11	77701991	Missense_Mutation	novel	F413C	0.07
READ	chr11	77702069	Missense_Mutation	novel	R387Q	0.07
READ	chr11	77667299	Missense_Mutation	novel	H1315R	0.24
READ	chr11	77725695	Nonsense_Mutation	NA	R195*	0.1
READ	chr11	77676907	Nonsense_Mutation	novel	R1076*	0.42
READ	chr11	77820695	Missense_Mutation	novel	A7V	0.2
READ	chr11	77667429	Nonsense_Mutation	NA	R1272*	0.37
READ	chr11	77675194	Missense_Mutation	novel	S1135Y	0.06
READ	chr11	77676865	Nonsense_Mutation	novel	R1090*	0.43
READ	chr11	77700917	Missense_Mutation	novel	V771A	0.35
READ	chr11	77701581	Missense_Mutation	NA	L550I	0.32
SARC	chr11	77764655	Silent	NA	L74L	0.36
SARC	chr11	77667429	Nonsense_Mutation	NA	R1272*	0.17
SARC	chr11	77667039	Missense_Mutation	novel	A1402T	0.41
SKCM	chr11	77667416	Missense_Mutation	NA	R1276Q	0.28
SKCM	chr11	77693563	Missense_Mutation	novel	R922C	0.37
SKCM	chr11	77666906	3'UTR	novel		0.57
SKCM	chr11	77672115	Silent	NA	S1226S	0.07
SKCM	chr11	77693563	Missense_Mutation	novel	R922C	0.68
SKCM	chr11	77701865	Missense_Mutation	NA	F455Y	0.17
SKCM	chr11	77698672	Nonsense_Mutation	NA	R844*	0.19
SKCM	chr11	77691167	Silent	rs139840785	A964A	0.26
SKCM	chr11	77676975	Missense_Mutation	NA	S1053F	0.39
SKCM	chr11	77700831	Nonsense_Mutation	NA	R800*	0.06
SKCM	chr11	77701071	Missense_Mutation	NA	E720K	0.55
SKCM	chr11	77700760	Silent	novel	L823L	0.36
SKCM	chr11	77701980	Missense_Mutation	NA	E417K	0.21
SKCM	chr11	77747102	Nonsense_Mutation	NA	W102*	0.16
SKCM	chr11	77698672	Nonsense_Mutation	NA	R844*	0.3
SKCM	chr11	77698581	Missense_Mutation	NA	S874L	0.41
SKCM	chr11	77701005	Missense_Mutation	rs142580915	R742W	0.06
SKCM	chr11	77701226	Missense_Mutation	NA	T668I	0.42
SKCM	chr11	77701921	Silent	novel	H436H	0.07
SKCM	chr11	77667354	Missense_Mutation	rs202106933	R1297C	0.37
SKCM	chr11	77701486	Silent	NA	I581I	0.33
SKCM	chr11	77701617	Missense_Mutation	NA	E538K	0.58
SKCM	chr11	77698556	Missense_Mutation	NA	S882R	0.43
SKCM	chr11	77676941	Silent	NA	S1064S	0.2
SKCM	chr11	77667356	Missense_Mutation	rs755685767	S1296F	0.54
SKCM	chr11	77740749	Nonsense_Mutation	novel	S187*	0.2
SKCM	chr11	77740826	Silent	NA	L161L	0.31
SKCM	chr11	77666906	3'UTR	novel		0.12
SKCM	chr11	77698672	Nonsense_Mutation	NA	R844*	0.23
SKCM	chr11	77701397	Missense_Mutation	NA	P611L	0.33
SKCM	chr11	77725695	Nonsense_Mutation	NA	R195*	0.44
SKCM	chr11	77740828	Missense_Mutation	NA	L161F	0.25
SKCM	chr11	77667126	Missense_Mutation	novel	G1373R	0.11
STAD	chr11	77698604	Silent	rs752652254	G866G	0.16
STAD	chr11	77675162	Missense_Mutation	NA	R1146C	0.2
STAD	chr11	77667303	Missense_Mutation	NA	A1314T	0.29
STAD	chr11	77667038	Missense_Mutation	NA	A1402E	0.2
STAD	chr11	77702071	Frame_Shift_Del	NA	*K386Nfs6**	0.18
STAD	chr11	77702071	Frame_Shift_Del	NA	*K386Nfs6**	0.44
STAD	chr11	77676992	Silent	NA	G1047G	0.25
STAD	chr11	77701086	Nonsense_Mutation	NA	E715*	0.38
STAD	chr11	77701754	Missense_Mutation	NA	S492Y	0.33
STAD	chr11	77702555	Intron	novel		0.22
STAD	chr11	77701785	Missense_Mutation	NA	T482P	0.33
STAD	chr11	77702408	Missense_Mutation	novel	T274I	0.36
STAD	chr11	77698500	Missense_Mutation	NA	N901T	0.08
STAD	chr11	77675238	Frame_Shift_Del	novel	*F1119Lfs29**	0.11
STAD	chr11	77675200	Missense_Mutation	rs200271333	P1133L	0.21
STAD	chr11	77666907	3'UTR	novel		0.29
STAD	chr11	77702071	Frame_Shift_Del	NA	*K386Nfs6**	0.3
STAD	chr11	77701274	Missense_Mutation	NA	S652N	0.69
STAD	chr11	77672183	Nonsense_Mutation	NA	R1204*	0.15
TGCT	chr11	77740915	Missense_Mutation	novel	D132H	0.34
THCA	chr11	77701731	Nonsense_Mutation	novel	*G500Ffs2**	0.06
THCA	chr11	77701799	Missense_Mutation	NA	D477G	0.32
UCEC	chr11	77667100	Silent	NA	E1381E	0.38
UCEC	chr11	77698617	Missense_Mutation	NA	S862N	0.37
UCEC	chr11	77701621	Missense_Mutation	NA	E536D	0.35
UCEC	chr11	77666916	3'UTR	novel		0.32
UCEC	chr11	77691230	Silent	NA	L943L	0.26
UCEC	chr11	77701513	Missense_Mutation	novel	K572N	0.09
UCEC	chr11	77764593	Splice_Region	novel		0.11
UCEC	chr11	77675085	Silent	rs550978468	Y1171Y	0.22
UCEC	chr11	77701213	Missense_Mutation	novel	D672E	0.29
UCEC	chr11	77702196	Missense_Mutation	novel	A345T	0.28
UCEC	chr11	77702488	Silent	novel	Q247Q	0.29
UCEC	chr11	77676958	Missense_Mutation	novel	R1059C	0.3
UCEC	chr11	77672101	Missense_Mutation	rs375867749	R1231Q	0.42
UCEC	chr11	77701584	Missense_Mutation	NA	D549Y	0.36
UCEC	chr11	77675169	Silent	novel	F1143F	0.5
UCEC	chr11	77700991	Silent	rs757797189	P746P	0.46
UCEC	chr11	77700830	Frame_Shift_Ins	novel	*R800Kfs7**	0.4
UCEC	chr11	77675200	Missense_Mutation	rs200271333	P1133L	0.4
UCEC	chr11	77701629	Missense_Mutation	novel	P534S	0.36
UCEC	chr11	77691172	Missense_Mutation	novel	R963S	0.46
UCEC	chr11	77698672	Nonsense_Mutation	NA	R844*	0.46
UCEC	chr11	77675051	Missense_Mutation	novel	N1183D	0.36
UCEC	chr11	77702175	Missense_Mutation	rs757424846	E352K	0.38
UCEC	chr11	77701375	Silent	novel	E618E	0.25
UCEC	chr11	77666662	3'UTR	novel		0.54
UCEC	chr11	77725694	Missense_Mutation	rs753571778	R195Q	0.2
UCEC	chr11	77740759	Missense_Mutation	NA	D184Y	0.39
UCEC	chr11	77740830	Missense_Mutation	NA	G160D	0.19
UCEC	chr11	77667423	Missense_Mutation	NA	R1274W	0.42
UCEC	chr11	77667408	Missense_Mutation	NA	D1279Y	0.19
UCEC	chr11	77700951	Nonsense_Mutation	novel	E760*	0.11
UCEC	chr11	77701778	Missense_Mutation	NA	G484E	0.26
UCEC	chr11	77676977	Silent	NA	I1052I	0.24
UCEC	chr11	77702188	Silent	rs780114893	E347E	0.19
UCEC	chr11	77740820	Nonsense_Mutation	novel	Y163*	0.22
UCEC	chr11	77676882	Missense_Mutation	rs752474632	R1084Q	0.33
UCEC	chr11	77667429	Nonsense_Mutation	NA	R1272*	0.07
UCEC	chr11	77700849	Nonsense_Mutation	novel	Q794*	0.37
UCEC	chr11	77667100	Missense_Mutation	novel	E1381D	0.41
UCEC	chr11	77667324	Nonsense_Mutation	novel	E1307*	0.3
UCEC	chr11	77698672	Nonsense_Mutation	NA	R844*	0.4
UCEC	chr11	77702226	Missense_Mutation	novel	D335Y	0.22
UCEC	chr11	77764681	Nonsense_Mutation	novel	E66*	0.3
UCEC	chr11	77672213	Missense_Mutation	novel	D1194N	0.44
UCEC	chr11	77747065	Missense_Mutation	novel	S115G	0.08
UCEC	chr11	77701054	Silent	rs146551886	T725T	0.42
UCEC	chr11	77702421	Missense_Mutation	rs754125186	V270I	0.34
UCEC	chr11	77740871	Silent	rs773193267	A146A	0.26
UCEC	chr11	77666938	Silent	novel	V1435V	0.38
UCEC	chr11	77700792	Missense_Mutation	novel	A813S	0.49
UCEC	chr11	77702146	Silent	NA	H361H	0.67
UCEC	chr11	77683808	Missense_Mutation	novel	F989L	0.5
UCEC	chr11	77676870	Missense_Mutation	rs765155596	R1088H	0.46
UCEC	chr11	77725651	Silent	NA	I209I	0.41
UCEC	chr11	77683769	Frame_Shift_Del	novel	*K1002Nfs18**	0.39
UCEC	chr11	77667438	Missense_Mutation	rs199889950	R1269W	0.44
UCEC	chr11	77702345	In_Frame_Ins	novel	K294_L295insQLLDIKKN	0.07
UCEC	chr11	77667096	Missense_Mutation	novel	L1383V	0.33
UCEC	chr11	77700913	Silent	novel	G772G	0.31
UCEC	chr11	77701874	Frame_Shift_Ins	novel	*A452Dfs6**	0.06
UCEC	chr11	77701875	In_Frame_Ins	novel	V451_A452insSRKVFL	0.06
UCEC	chr11	77701145	Missense_Mutation	novel	S695C	0.15
UCEC	chr11	77702232	Missense_Mutation	novel	P333S	0.3
UCEC	chr11	77672102	Nonsense_Mutation	NA	R1231*	0.51
UCEC	chr11	77702309	Missense_Mutation	novel	I307S	0.33
UCEC	chr11	77666705	3'UTR	novel		0.48
UCEC	chr11	77667138	Missense_Mutation	novel	P1369S	0.47
UCEC	chr11	77675117	Missense_Mutation	NA	R1161C	0.08
UCEC	chr11	77701065	Missense_Mutation	rs750957158	T722A	0.11
UCEC	chr11	77702175	Missense_Mutation	rs757424846	E352K	0.13
UCEC	chr11	77740890	Missense_Mutation	novel	I140T	0.3
UCEC	chr11	77702071	Missense_Mutation	novel	K386N	0.44
UCEC	chr11	77667423	Missense_Mutation	NA	R1274W	0.31
UCEC	chr11	77698650	Missense_Mutation	NA	R851H	0.33
UCEC	chr11	77667376	Silent	rs746329540	E1289E	0.3
UCEC	chr11	77701450	Frame_Shift_Ins	novel	*T594Dfs4**	0.41
UCEC	chr11	77666612	3'UTR	novel		0.33
UCEC	chr11	77675110	Missense_Mutation	rs145881006	R1163Q	0.31
UCEC	chr11	77666660	3'UTR	novel		0.36
UCEC	chr11	77672153	Nonsense_Mutation	novel	Q1214*	0.42
UCEC	chr11	77702631	Intron	novel		0.29
UCEC	chr11	77725700	Splice_Site	novel	X193_splice	0.15
UCS	chr11	77701798	Missense_Mutation	novel	D477E	0.09

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BRCA	AMP	0.2111	8.3616e-65
ESCA	AMP	0.212	0.018342
TGCT	DEL	0.6933	0.21504
UCEC	AMP	0.0853	8.2209e-05

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
ACC	0.0019	Kaplan-Meier Survival Analysis
UCS	0.041	Kaplan-Meier Survival Analysis
PRAD	0.025	Kaplan-Meier Survival Analysis
PAAD	0.00051	Kaplan-Meier Survival Analysis
READ	0.05	Kaplan-Meier Survival Analysis
KICH	0.046	Kaplan-Meier Survival Analysis
UCEC	0.0033	Kaplan-Meier Survival Analysis
GBM	0.017	Kaplan-Meier Survival Analysis
LIHC	0.018	Kaplan-Meier Survival Analysis
LGG	0.0032	Kaplan-Meier Survival Analysis
OV	0.029	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000048649 (Gene tree)
Gene ID: 51773
Gene Symbol: RSF1
Alias: XAP8|RSF-1|p325|HBXAP
Full Name: remodeling and spacing factor 1
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 161,022 bases
Position: chr11:77,659,996-77,821,017
Accession: 18118
Summary: This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
10325428	Recognition of exonic splicing enhancer sequences by the Drosophila splicing repressor RSF1.	Nucleic Acids Res	1999 Jun 1	Labourier E	-
10090730	Antagonism between RSF1 and SR proteins for both splice-site recognition in vitro and Drosophila development.	Genes Dev	1999 Mar 15	Labourier E	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000480887	RSF1-204	5318	-	ENSP00000434509	1189 (aa)	-	Q96T23
ENST00000467567	RSF1-203	2982	-	-	- (aa)	-	-
ENST00000534794	RSF1-212	487	-	-	- (aa)	-	-
ENST00000529470	RSF1-207	448	-	-	- (aa)	-	-
ENST00000440064	RSF1-202	604	-	ENSP00000408844	202 (aa)	-	H7C306
ENST00000531768	RSF1-210	626	-	-	- (aa)	-	-
ENST00000530604	RSF1-208	520	-	-	- (aa)	-	-
ENST00000308488	RSF1-201	11550	XM_005274051	ENSP00000311513	1441 (aa)	XP_005274108	Q96T23
ENST00000526324	RSF1-205	2409	-	ENSP00000432022	803 (aa)	-	H0YCN2
ENST00000531026	RSF1-209	830	-	ENSP00000433603	276 (aa)	-	H0YDG9
ENST00000528095	RSF1-206	2107	-	ENSP00000436408	702 (aa)	-	H0YER1
ENST00000532556	RSF1-211	495	-	ENSP00000436728	165 (aa)	-	H0YEX0

Gene Model

Click here to download ENSG00000048649's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000048649	rs1045590	11	77665761	?	Menarche (age at onset)	30595370			EFO_0004703

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000048649's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000048649	RSF1	100	97.826	ENSMUSG00000035623	Rsf1	99	82.809	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000123	histone acetyltransferase complex	21873635.	IBA	Component
GO:0000790	nuclear chromatin	21873635.	IBA	Component
GO:0004402	histone acetyltransferase activity	21873635.	IBA	Function
GO:0005515	protein binding	12972596.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	11788598.12972596.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006334	nucleosome assembly	12972596.	IDA	Process
GO:0006338	chromatin remodeling	9836642.	IDA	Process
GO:0006352	DNA-templated transcription, initiation	9836642.	IDA	Process
GO:0016573	histone acetylation	-	IEA	Process
GO:0016584	nucleosome positioning	9836642.	IDA	Process
GO:0016887	ATPase activity	12972596.	IDA	Function
GO:0031213	RSF complex	9836642.	IPI	Component
GO:0034080	CENP-A containing nucleosome assembly	-	TAS	Process
GO:0042393	histone binding	21873635.	IBA	Function
GO:0042393	histone binding	12972596.	IDA	Function
GO:0043392	negative regulation of DNA binding	12972596.	IDA	Process
GO:0045892	negative regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0045892	negative regulation of transcription, DNA-templated	11944984.	IDA	Process
GO:0045893	positive regulation of transcription, DNA-templated	11788598.	IDA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0050434	positive regulation of viral transcription	11788598.	IDA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

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Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.