EuRBPDB

Note: to get the extension of tumor abbreviations.

Cancer Related Information
Basic Information

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
21646684	Molecular signature induced by RNASET2, a tumor antagonizing gene, in ovarian cancer cells.	Oncotarget	2011 Jun	Acquati F	-
15809705	Tumor and metastasis suppression by the human RNASET2 gene.	Int J Oncol	2005 May	Acquati F	-
21446958	Comparison of the baculovirus-insect cell and Pichia pastoris heterologous systems for the expression of the human tumor suppressor protein RNASET2.	Biotechnol Appl Biochem	2011 Jan-Feb	Campomenosi P	doi: 10.1002/bab.7.
24842157	Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer.	Oncol Rep	2014 Jul	Yin F	doi: 10.3892/or.2014.3175

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr6	166938969	Silent	NA	Q124Q	0.09
BLCA	chr6	166943056	Missense_Mutation	novel	D99N	0.24
BLCA	chr6	166938592	Intron	novel		0.4
BLCA	chr6	166929645	Silent	novel	L238L	0.17
BLCA	chr6	166952502	Missense_Mutation	novel	E45Q	0.08	Ribonuclease_T2
BRCA	chr6	166934042	Intron	novel		0.08
BRCA	chr6	166934156	Intron	novel		0.18
BRCA	chr6	166952538	Missense_Mutation	NA	E33K	0.15
BRCA	chr6	166934282	Intron	novel		0.29
BRCA	chr6	166929518	3'Flank	rs765918162		0.2
BRCA	chr6	166931078	Missense_Mutation	novel	V178E	0.13
CESC	chr6	166943725	Intron	NA		0.46
CESC	chr6	166929674	Missense_Mutation	novel	A229T	0.36
CESC	chr6	166938745	Intron	novel		0.14
CESC	chr6	166934064	Intron	NA		0.22
CHOL	chr6	166938630	Intron	novel		0.24
COAD	chr6	166929550	3'UTR	novel		0.32
COAD	chr6	166931061	Missense_Mutation	novel	C184S	0.64
COAD	chr6	166934137	Splice_Site	NA	X149_splice	0.27
COAD	chr6	166931059	Nonsense_Mutation	novel	C184*	0.06
COAD	chr6	166938961	Missense_Mutation	rs117003826	A127V	0.36
COAD	chr6	166938961	Missense_Mutation	rs117003826	A127V	0.33
COAD	chr6	166938796	Intron	novel		0.5
COAD	chr6	166931093	Missense_Mutation	NA	A173V	0.13
COAD	chr6	166943701	Intron	novel		0.38
COAD	chr6	166952527	Frame_Shift_Del	novel	*K36Nfs2**	0.35	Ribonuclease_T2
COAD	chr6	166943758	Intron	novel		0.18
GBM	chr6	166938911	Missense_Mutation	novel	E144Q	0.11
GBM	chr6	166946710	Missense_Mutation	novel	S78L	0.45	Ribonuclease_T2
GBM	chr6	166943086	Missense_Mutation	novel	L89F	0.59	Ribonuclease_T2
GBM	chr6	166938883	Intron	novel		0.48
HNSC	chr6	166929659	Missense_Mutation	rs754474033	E234K	0.26
HNSC	chr6	166929652	Missense_Mutation	rs146590748	R236Q	0.05
HNSC	chr6	166938850	Intron	novel		0.06
HNSC	chr6	166931077	Silent	novel	V178V	0.24
LAML	chr6	166929753	Silent	novel	C202C	0.08
LIHC	chr6	166952547	Missense_Mutation	NA	D30N	0.13
LUAD	chr6	166938604	Intron	novel		0.2
LUAD	chr6	166938997	Missense_Mutation	novel	W115L	0.15
LUAD	chr6	166931043	Splice_Site	NA	X189_splice	0.18
LUSC	chr6	166934133	Silent	rs747165370	V150V	0.15
LUSC	chr6	166952492	Missense_Mutation	novel	C48Y	0.19	Ribonuclease_T2
LUSC	chr6	166929657	Silent	novel	E234E	0.25
MESO	chr6	166929766	Missense_Mutation	novel	Q198L	0.05
OV	chr6	166952500	Missense_Mutation	novel	E45D	0.1	Ribonuclease_T2
OV	chr6	166938757	Intron	novel		0.69
OV	chr6	166929785	Nonsense_Mutation	novel	E191_E192ins*	0.1
OV	chr6	166938853	Intron	novel		0.08
OV	chr6	166952497	Silent	novel	T46T	0.21
PAAD	chr6	166931044	Missense_Mutation	novel	Q189H	0.2
READ	chr6	166929548	3'UTR	novel		0.26
READ	chr6	166934156	Intron	novel		0.2
READ	chr6	166931103	Missense_Mutation	novel	D170Y	0.46
SKCM	chr6	166938611	Intron	novel		0.28
SKCM	chr6	166938579	Intron	novel		0.53
SKCM	chr6	166934053	Intron	novel		0.63
SKCM	chr6	166938581	Intron	novel		0.12
SKCM	chr6	166938742	Intron	NA		0.12
SKCM	chr6	166938615	Intron	novel		0.26
SKCM	chr6	166929612	Silent	rs76894173	P249P	0.29
SKCM	chr6	166938752	Intron	novel		0.35
SKCM	chr6	166938951	Silent	NA	S130S	0.14
SKCM	chr6	166948598	Missense_Mutation	NA	P59S	0.07	Ribonuclease_T2
SKCM	chr6	166929568	3'UTR	novel		0.2
SKCM	chr6	166933979	Intron	novel		0.32
SKCM	chr6	166938821	Intron	novel		0.83
SKCM	chr6	166933963	Intron	novel		0.32
SKCM	chr6	166929710	Missense_Mutation	rs753772218	G217R	0.18
SKCM	chr6	166929696	Silent	NA	S221S	0.41
STAD	chr6	166943180	Intron	novel		0.56
STAD	chr6	166938977	Missense_Mutation	rs763299296	A122T	0.21
STAD	chr6	166929519	3'Flank	novel		0.17
UCEC	chr6	166946688	Missense_Mutation	NA	E85D	0.33	Ribonuclease_T2
UCEC	chr6	166934190	Intron	novel		0.22
UCEC	chr6	166934030	Intron	novel		0.33
UCEC	chr6	166934057	Intron	novel		0.32
UCEC	chr6	166948611	Missense_Mutation	novel	D54E	0.38	Ribonuclease_T2
UCEC	chr6	166933993	Intron	novel		0.3
UCEC	chr6	166946726	Missense_Mutation	novel	E73K	0.32	Ribonuclease_T2
UCEC	chr6	166929594	Missense_Mutation	novel	K255N	0.11
UCEC	chr6	166929628	Missense_Mutation	novel	G244D	0.27
UCEC	chr6	166934141	Splice_Region	novel		0.33
UCEC	chr6	166952526	Frame_Shift_Ins	novel	*L37Tfs9**	0.58	Ribonuclease_T2
UCEC	chr6	166934142	Splice_Region	novel		0.42
UCEC	chr6	166929548	3'UTR	novel		0.52
UCEC	chr6	166929548	3'UTR	novel		0.34
UCEC	chr6	166946690	Nonsense_Mutation	novel	E85*	0.25	Ribonuclease_T2
UCEC	chr6	166929581	3'UTR	rs761431627		0.37
UCEC	chr6	166938626	Intron	novel		0.14
UCEC	chr6	166946710	Nonsense_Mutation	novel	S78*	0.43	Ribonuclease_T2
UCEC	chr6	166946731	Missense_Mutation	novel	K71T	0.13	Ribonuclease_T2
UCEC	chr6	166938940	Missense_Mutation	novel	Y134C	0.5
UCEC	chr6	166931094	Missense_Mutation	NA	A173T	0.31
UCEC	chr6	166938631	Intron	novel		0.3
UCEC	chr6	166943643	Intron	novel		0.38
UCEC	chr6	166933927	Intron	novel		0.19
UCEC	chr6	166938961	Missense_Mutation	rs117003826	A127V	0.33
UCEC	chr6	166938741	Intron	novel		0.27
UCS	chr6	166938672	Intron	novel		0.28

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.2	0.041315
BLCA	DEL	0.3775	0.00027473
CESC	DEL	0.2881	9.8477e-05
KIRC	DEL	0.2443	7.439e-11
KIRP	DEL	0.1076	0.054498
LGG	DEL	0.1404	0.0022414
MESO	DEL	0.3448	0.0023534
PAAD	DEL	0.375	0.11274
SKCM	DEL	0.5395	1.5442e-06
THYM	DEL	0.1382	0.10691

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00011	Kaplan-Meier Survival Analysis
SARC	0.032	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
PRAD	0.012	Kaplan-Meier Survival Analysis
ESCA	0.0044	Kaplan-Meier Survival Analysis
BLCA	0.0097	Kaplan-Meier Survival Analysis
LIHC	0.026	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
UVM	0.0049	Kaplan-Meier Survival Analysis

Drugs

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Description

Ensembl ID: ENSG00000026297 (Gene tree)
Gene ID: 8635
Gene Symbol: RNASET2
Alias: RNASE6PL|FLJ10907|bA514O12.3
Full Name: ribonuclease T2
Gene Type: protein_coding
Specie: Homo_sapiens
Strand: Minus strand
Length: 27,688 bases
Position: chr6:166,929,504-166,957,191
Accession: 21686
Summary: This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000426059	Ribonuclease_T2	PF00445.18	5.1e-59	1	1
ENSP00000422846	Ribonuclease_T2	PF00445.18	5.2e-59	1	1
ENSP00000426455	Ribonuclease_T2	PF00445.18	5.2e-59	1	1
ENSP00000482755	Ribonuclease_T2	PF00445.18	1.9e-57	1	1
ENSP00000424947	Ribonuclease_T2	PF00445.18	2.1e-57	1	1
ENSP00000480244	Ribonuclease_T2	PF00445.18	8.3e-14	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000476238	RNASET2-206	887	-	ENSP00000422846	256 (aa)	-	O00584
ENST00000421787	RNASET2-204	1924	-	ENSP00000390833	121 (aa)	-	O00584
ENST00000620173	RNASET2-214	1391	-	ENSP00000482755	306 (aa)	-	A0A087WZM2
ENST00000496851	RNASET2-208	881	-	-	- (aa)	-	-
ENST00000510083	RNASET2-212	2280	-	-	- (aa)	-	-
ENST00000028008	RNASET2-201	1220	-	ENSP00000028008	71 (aa)	-	J3QQ64
ENST00000509073	RNASET2-211	433	-	-	- (aa)	-	-
ENST00000467705	RNASET2-205	524	-	-	- (aa)	-	-
ENST00000358165	RNASET2-202	2445	-	-	- (aa)	-	-
ENST00000366855	RNASET2-203	1417	XM_017011397	ENSP00000424947	218 (aa)	XP_016866886	D6REQ6
ENST00000478180	RNASET2-207	963	-	ENSP00000426059	253 (aa)	-	D6RHI9
ENST00000499370	RNASET2-209	2164	-	-	- (aa)	-	-
ENST00000611959	RNASET2-213	1124	-	ENSP00000480244	238 (aa)	-	A0A087WWI1
ENST00000508775	RNASET2-210	1375	XM_017011399	ENSP00000426455	256 (aa)	XP_016866888	O00584

Gene Model

Click here to download 's gene model file

Phenotype

ensgID	Trait	pValue	Pubmed ID
ENSG00000026297	Inflammatory Bowel Diseases	9E-15	28067908
ENSG00000026297	Dental Caries	7E-6	24556642
ENSG00000026297	Vitiligo	1E-16	20526339
ENSG00000026297	Crohn Disease	2E-20	28067908
ENSG00000026297	Inflammatory Bowel Diseases	1E-6	27569725
ENSG00000026297	Inflammatory Bowel Diseases	2E-17	26192919
ENSG00000026297	Graves Disease	7E-10	21841780
ENSG00000026297	Premature Birth	1E-9	25599974
ENSG00000026297	Live Birth	1E-9	25599974
ENSG00000026297	Crohn Disease	8E-12	23850713
ENSG00000026297	Crohn Disease	3E-12	21102463
ENSG00000026297	Inflammatory Bowel Diseases	7E-21	23128233
ENSG00000026297	Crohn Disease	2E-19	26192919
ENSG00000026297	Carcinoma, Basal Cell	1E-8	27539887
ENSG00000026297	Crohn Disease	2E-18	26192919

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000026297	rs3777722	6	166938616	?	Spontaneous preterm birth (preterm birth)	25599974	[NR]	1.64	EFO_0006921\|EFO_0006917
ENSG00000026297	rs3798305	6	166949985	T	Smooth-surface caries	24556642	[NR] unit increase	4.8339	EFO_0006339
ENSG00000026297	rs2236313	6	166946901	T	Vitiligo	20526339	[1.15-1.25]	1.2	EFO_0004208
ENSG00000026297	rs2247314	6	166956742	T	Vitiligo	27723757	[1.19-1.33]	1.2597632	EFO_0004208
ENSG00000026297	rs117933444	6	166949385	?	Huntington's disease progression	28642124			Orphanet_399\|EFO_0008336

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000026297's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy	Species
ENSG00000026297	RNASET2	97	45.327	ENSAPOG00000011704	rnaset2	89	45.701	Acanthochromis_polyacanthus
ENSG00000026297	RNASET2	50	35.455	ENSAPOG00000012996	rnaset2l	64	35.965	Acanthochromis_polyacanthus
ENSG00000026297	RNASET2	100	72.477	ENSAMEG00000009382	-	87	73.451	Ailuropoda_melanoleuca
ENSG00000026297	RNASET2	98	45.370	ENSAOCG00000023510	rnaset2	90	46.188	Amphiprion_ocellaris
ENSG00000026297	RNASET2	50	39.286	ENSAOCG00000016221	rnaset2l	62	36.434	Amphiprion_ocellaris
ENSG00000026297	RNASET2	69	37.179	ENSAPEG00000021153	rnaset2l	60	36.364	Amphiprion_percula
ENSG00000026297	RNASET2	98	44.907	ENSAPEG00000007551	rnaset2	90	45.740	Amphiprion_percula
ENSG00000026297	RNASET2	69	33.974	ENSATEG00000002741	rnaset2l	62	33.333	Anabas_testudineus
ENSG00000026297	RNASET2	97	45.540	ENSATEG00000022393	rnaset2	97	42.640	Anabas_testudineus
ENSG00000026297	RNASET2	97	61.972	ENSAPLG00000010821	-	85	62.273	Anas_platyrhynchos
ENSG00000026297	RNASET2	100	54.587	ENSACAG00000010505	-	83	54.222	Anolis_carolinensis
ENSG00000026297	RNASET2	96	91.176	ENSANAG00000025875	-	100	86.719	Aotus_nancymaae
ENSG00000026297	RNASET2	97	42.523	ENSACLG00000008102	rnaset2	91	42.222	Astatotilapia_calliptera
ENSG00000026297	RNASET2	84	32.468	ENSACLG00000011085	rnaset2l	78	33.645	Astatotilapia_calliptera
ENSG00000026297	RNASET2	69	41.026	ENSAMXG00000042594	rnaset2l	64	39.766	Astyanax_mexicanus
ENSG00000026297	RNASET2	97	46.009	ENSAMXG00000034683	rnaset2	88	45.333	Astyanax_mexicanus
ENSG00000026297	RNASET2	99	59.633	ENSBTAG00000014494	RNASET2	89	59.912	Bos_taurus
ENSG00000026297	RNASET2	78	86.391	ENSCJAG00000000469	-	100	86.391	Callithrix_jacchus
ENSG00000026297	RNASET2	100	72.222	ENSCAFG00000000842	-	98	69.685	Canis_familiaris
ENSG00000026297	RNASET2	98	73.953	ENSCAFG00020019344	-	54	69.685	Canis_lupus_dingo
ENSG00000026297	RNASET2	99	55.963	ENSCHIG00000021432	-	99	56.696	Capra_hircus
ENSG00000026297	RNASET2	100	83.486	ENSTSYG00000002788	-	100	83.486	Carlito_syrichta
ENSG00000026297	RNASET2	100	63.470	ENSCPOG00000007899	-	89	64.317	Cavia_porcellus
ENSG00000026297	RNASET2	100	85.375	ENSCCAG00000022079	-	100	85.156	Cebus_capucinus
ENSG00000026297	RNASET2	96	97.059	ENSCATG00000009971	RNASET2	100	88.925	Cercocebus_atys
ENSG00000026297	RNASET2	100	66.055	ENSCLAG00000005811	-	88	66.814	Chinchilla_lanigera
ENSG00000026297	RNASET2	100	97.248	ENSCSAG00000012144	RNASET2	100	97.248	Chlorocebus_sabaeus
ENSG00000026297	RNASET2	100	61.111	ENSCHOG00000004204	-	89	54.701	Choloepus_hoffmanni
ENSG00000026297	RNASET2	77	33.816	ENSCPBG00000006878	-	70	35.057	Chrysemys_picta_bellii
ENSG00000026297	RNASET2	99	61.751	ENSCPBG00000012576	-	66	63.303	Chrysemys_picta_bellii
ENSG00000026297	RNASET2	85	35.683	ENSCING00000022590	-	79	36.869	Ciona_intestinalis
ENSG00000026297	RNASET2	81	38.830	ENSCSAVG00000006636	-	73	38.071	Ciona_savignyi
ENSG00000026297	RNASET2	100	96.330	ENSCANG00000030094	RNASET2	100	95.312	Colobus_angolensis_palliatus
ENSG00000026297	RNASET2	100	73.394	ENSCGRG00001024749	-	86	73.894	Cricetulus_griseus_chok1gshd
ENSG00000026297	RNASET2	100	73.394	ENSCGRG00000011844	-	86	73.894	Cricetulus_griseus_crigri
ENSG00000026297	RNASET2	59	37.313	ENSCSEG00000015722	rnaset2l	56	37.063	Cynoglossus_semilaevis
ENSG00000026297	RNASET2	97	44.907	ENSCSEG00000013249	rnaset2	88	45.455	Cynoglossus_semilaevis
ENSG00000026297	RNASET2	97	31.982	ENSCVAG00000007485	rnaset2l	79	31.624	Cyprinodon_variegatus
ENSG00000026297	RNASET2	97	45.982	ENSCVAG00000019247	rnaset2	88	46.725	Cyprinodon_variegatus
ENSG00000026297	RNASET2	97	45.622	ENSDARG00000036282	rnaset2	88	46.637	Danio_rerio
ENSG00000026297	RNASET2	86	33.816	ENSDARG00000058413	rnaset2l	93	32.883	Danio_rerio
ENSG00000026297	RNASET2	99	72.811	ENSDNOG00000015061	-	99	70.312	Dasypus_novemcinctus
ENSG00000026297	RNASET2	100	55.046	ENSDORG00000011636	-	99	56.637	Dipodomys_ordii
ENSG00000026297	RNASET2	77	31.285	FBgn0010406	RNaseX25	57	31.915	Drosophila_melanogaster
ENSG00000026297	RNASET2	77	44.509	ENSEBUG00000003096	rnaset2	86	38.158	Eptatretus_burgeri
ENSG00000026297	RNASET2	100	74.886	ENSEASG00005000345	-	88	74.890	Equus_asinus_asinus
ENSG00000026297	RNASET2	55	75.630	ENSECAG00000016754	-	60	75.630	Equus_caballus
ENSG00000026297	RNASET2	98	45.116	ENSELUG00000019269	RNT2	87	45.455	Esox_lucius
ENSG00000026297	RNASET2	79	34.928	ENSELUG00000011452	rnaset2l	66	38.068	Esox_lucius
ENSG00000026297	RNASET2	99	69.124	ENSFCAG00000031545	-	89	70.354	Felis_catus
ENSG00000026297	RNASET2	100	57.078	ENSFALG00000012299	-	87	57.269	Ficedula_albicollis
ENSG00000026297	RNASET2	75	59.756	ENSFDAG00000015906	-	100	59.756	Fukomys_damarensis
ENSG00000026297	RNASET2	73	37.195	ENSFHEG00000012418	rnaset2l	76	32.900	Fundulus_heteroclitus
ENSG00000026297	RNASET2	97	47.664	ENSFHEG00000020292	rnaset2	86	48.402	Fundulus_heteroclitus
ENSG00000026297	RNASET2	97	43.925	ENSGMOG00000012328	rnaset2	98	44.091	Gadus_morhua
ENSG00000026297	RNASET2	99	57.339	ENSGALG00000011426	RNASET2	83	57.778	Gallus_gallus
ENSG00000026297	RNASET2	97	48.826	ENSGAFG00000002683	rnaset2	86	49.541	Gambusia_affinis
ENSG00000026297	RNASET2	75	36.471	ENSGAFG00000018686	rnaset2l	67	35.135	Gambusia_affinis
ENSG00000026297	RNASET2	99	42.922	ENSGACG00000016041	rnaset2	88	43.805	Gasterosteus_aculeatus
ENSG00000026297	RNASET2	97	63.033	ENSGAGG00000021141	-	84	63.303	Gopherus_agassizii
ENSG00000026297	RNASET2	77	33.333	ENSGAGG00000019255	-	70	33.908	Gopherus_agassizii
ENSG00000026297	RNASET2	100	100.000	ENSGGOG00000000498	RNASET2	100	99.609	Gorilla_gorilla
ENSG00000026297	RNASET2	99	79.263	ENSGGOG00000023732	-	96	79.263	Gorilla_gorilla
ENSG00000026297	RNASET2	97	42.523	ENSHBUG00000000503	rnaset2	79	42.222	Haplochromis_burtoni
ENSG00000026297	RNASET2	92	65.236	ENSHGLG00000002675	-	81	67.980	Heterocephalus_glaber_female
ENSG00000026297	RNASET2	100	66.972	ENSHGLG00100007745	-	88	67.699	Heterocephalus_glaber_male
ENSG00000026297	RNASET2	97	45.794	ENSHCOG00000014900	rnaset2	90	46.606	Hippocampus_comes
ENSG00000026297	RNASET2	73	37.195	ENSIPUG00000007500	rnaset2l	67	36.184	Ictalurus_punctatus
ENSG00000026297	RNASET2	99	46.330	ENSIPUG00000017307	rnaset2	88	46.875	Ictalurus_punctatus
ENSG00000026297	RNASET2	99	72.811	ENSSTOG00000010853	-	99	73.333	Ictidomys_tridecemlineatus
ENSG00000026297	RNASET2	99	71.889	ENSJJAG00000013485	-	99	72.444	Jaculus_jaculus
ENSG00000026297	RNASET2	97	43.192	ENSKMAG00000020963	rnaset2	89	43.119	Kryptolebias_marmoratus
ENSG00000026297	RNASET2	75	33.728	ENSLBEG00000016204	-	76	35.465	Labrus_bergylta
ENSG00000026297	RNASET2	99	44.344	ENSLBEG00000001745	rnaset2	81	45.133	Labrus_bergylta
ENSG00000026297	RNASET2	97	49.296	ENSLACG00000014464	-	85	49.772	Latimeria_chalumnae
ENSG00000026297	RNASET2	55	39.344	ENSLOCG00000014694	rnaset2l	76	37.405	Lepisosteus_oculatus
ENSG00000026297	RNASET2	100	44.749	ENSLOCG00000016824	rnaset2	89	45.291	Lepisosteus_oculatus
ENSG00000026297	RNASET2	99	69.302	ENSLAFG00000003359	-	99	70.000	Loxodonta_africana
ENSG00000026297	RNASET2	100	96.443	ENSMFAG00000039774	RNASET2	100	96.094	Macaca_fascicularis
ENSG00000026297	RNASET2	100	96.443	ENSMMUG00000005673	RNASET2	100	96.094	Macaca_mulatta
ENSG00000026297	RNASET2	100	85.388	ENSMNEG00000033732	RNASET2	100	85.388	Macaca_nemestrina
ENSG00000026297	RNASET2	100	96.330	ENSMLEG00000020984	RNASET2	100	96.476	Mandrillus_leucophaeus
ENSG00000026297	RNASET2	97	44.393	ENSMAMG00000020321	rnaset2	87	45.205	Mastacembelus_armatus
ENSG00000026297	RNASET2	75	31.000	ENSMAMG00000019809	rnaset2l	63	33.133	Mastacembelus_armatus
ENSG00000026297	RNASET2	97	42.523	ENSMZEG00005011825	rnaset2	91	42.222	Maylandia_zebra
ENSG00000026297	RNASET2	84	32.468	ENSMZEG00005000076	rnaset2l	78	33.645	Maylandia_zebra
ENSG00000026297	RNASET2	97	59.906	ENSMGAG00000012305	-	81	60.000	Meleagris_gallopavo
ENSG00000026297	RNASET2	100	71.101	ENSMAUG00000000335	-	86	72.000	Mesocricetus_auratus
ENSG00000026297	RNASET2	100	77.523	ENSMICG00000014184	-	100	76.953	Microcebus_murinus
ENSG00000026297	RNASET2	99	69.124	ENSMOCG00000016647	-	86	69.778	Microtus_ochrogaster
ENSG00000026297	RNASET2	90	46.465	ENSMMOG00000015983	rnaset2	93	46.465	Mola_mola
ENSG00000026297	RNASET2	55	38.211	ENSMMOG00000009779	rnaset2l	55	37.594	Mola_mola
ENSG00000026297	RNASET2	99	66.667	ENSMODG00000006193	-	87	67.857	Monodelphis_domestica
ENSG00000026297	RNASET2	75	32.500	ENSMALG00000017923	rnaset2l	63	34.940	Monopterus_albus
ENSG00000026297	RNASET2	97	44.601	ENSMALG00000010836	rnaset2	84	45.455	Monopterus_albus
ENSG00000026297	RNASET2	100	72.018	MGP_CAROLIEiJ_G0021068	-	86	72.566	Mus_caroli
ENSG00000026297	RNASET2	100	72.018	MGP_CAROLIEiJ_G0021069	-	86	72.566	Mus_caroli
ENSG00000026297	RNASET2	100	71.101	ENSMUSG00000094724	Rnaset2b	100	73.171	Mus_musculus
ENSG00000026297	RNASET2	100	71.101	ENSMUSG00000095687	Rnaset2a	86	71.681	Mus_musculus
ENSG00000026297	RNASET2	100	69.266	MGP_PahariEiJ_G0023385	-	87	70.354	Mus_pahari
ENSG00000026297	RNASET2	100	69.266	MGP_PahariEiJ_G0023386	-	87	70.354	Mus_pahari
ENSG00000026297	RNASET2	100	71.101	MGP_SPRETEiJ_G0021950	-	86	71.681	Mus_spretus
ENSG00000026297	RNASET2	100	71.101	MGP_SPRETEiJ_G0021951	-	86	71.681	Mus_spretus
ENSG00000026297	RNASET2	99	61.404	ENSMPUG00000006468	-	86	63.063	Mustela_putorius_furo
ENSG00000026297	RNASET2	99	73.733	ENSNGAG00000014822	-	86	73.778	Nannospalax_galili
ENSG00000026297	RNASET2	97	42.523	ENSNBRG00000006817	rnaset2	91	42.222	Neolamprologus_brichardi
ENSG00000026297	RNASET2	61	33.333	ENSNBRG00000004966	rnaset2l	51	38.462	Neolamprologus_brichardi
ENSG00000026297	RNASET2	100	98.165	ENSNLEG00000027795	RNASET2	100	98.165	Nomascus_leucogenys
ENSG00000026297	RNASET2	100	47.706	ENSMEUG00000009644	-	72	78.947	Notamacropus_eugenii
ENSG00000026297	RNASET2	99	67.907	ENSODEG00000002506	-	88	68.610	Octodon_degus
ENSG00000026297	RNASET2	97	42.523	ENSONIG00000005526	rnaset2	91	42.222	Oreochromis_niloticus
ENSG00000026297	RNASET2	83	33.679	ENSONIG00000001097	rnaset2l	79	33.333	Oreochromis_niloticus
ENSG00000026297	RNASET2	97	66.509	ENSOANG00000022585	-	88	65.625	Ornithorhynchus_anatinus
ENSG00000026297	RNASET2	73	35.976	ENSORLG00000028892	rnaset2l	73	34.694	Oryzias_latipes
ENSG00000026297	RNASET2	97	46.759	ENSORLG00000029310	rnaset2	90	47.321	Oryzias_latipes
ENSG00000026297	RNASET2	97	45.833	ENSORLG00020001092	rnaset2	90	46.429	Oryzias_latipes_hni
ENSG00000026297	RNASET2	73	36.585	ENSORLG00020021649	rnaset2l	73	35.204	Oryzias_latipes_hni
ENSG00000026297	RNASET2	97	44.860	ENSORLG00015002971	rnaset2	88	45.662	Oryzias_latipes_hsok
ENSG00000026297	RNASET2	73	35.976	ENSORLG00015010635	rnaset2l	73	34.694	Oryzias_latipes_hsok
ENSG00000026297	RNASET2	83	35.602	ENSOMEG00000019739	rnaset2l	69	35.000	Oryzias_melastigma
ENSG00000026297	RNASET2	97	46.262	ENSOMEG00000004209	rnaset2	90	46.847	Oryzias_melastigma
ENSG00000026297	RNASET2	99	82.949	ENSOGAG00000006308	-	88	83.186	Otolemur_garnettii
ENSG00000026297	RNASET2	99	60.550	ENSOARG00000004909	-	96	60.793	Ovis_aries
ENSG00000026297	RNASET2	100	99.209	ENSPPAG00000031557	RNASET2	99	99.216	Pan_paniscus
ENSG00000026297	RNASET2	99	69.124	ENSPPRG00000005136	-	89	70.354	Panthera_pardus
ENSG00000026297	RNASET2	83	73.889	ENSPTIG00000010220	-	82	75.132	Panthera_tigris_altaica
ENSG00000026297	RNASET2	100	100.000	ENSPTRG00000018796	RNASET2	100	99.219	Pan_troglodytes
ENSG00000026297	RNASET2	100	97.233	ENSPANG00000022370	RNASET2	100	96.875	Papio_anubis
ENSG00000026297	RNASET2	96	33.796	ENSPKIG00000006201	rnaset2l	86	32.889	Paramormyrops_kingsleyae
ENSG00000026297	RNASET2	99	44.495	ENSPKIG00000014931	rnaset2	76	45.374	Paramormyrops_kingsleyae
ENSG00000026297	RNASET2	98	50.000	ENSPSIG00000003026	-	88	50.521	Pelodiscus_sinensis
ENSG00000026297	RNASET2	90	43.147	ENSPMGG00000000517	rnaset2	97	43.147	Periophthalmus_magnuspinnatus
ENSG00000026297	RNASET2	100	70.642	ENSPEMG00000011035	-	92	71.053	Peromyscus_maniculatus_bairdii
ENSG00000026297	RNASET2	84	39.474	ENSPMAG00000007584	rnaset2	78	39.500	Petromyzon_marinus
ENSG00000026297	RNASET2	99	71.296	ENSPCIG00000000971	-	83	71.239	Phascolarctos_cinereus
ENSG00000026297	RNASET2	95	32.864	ENSPFOG00000000682	-	80	32.018	Poecilia_formosa
ENSG00000026297	RNASET2	95	33.333	ENSPLAG00000013085	rnaset2l	80	32.456	Poecilia_latipinna
ENSG00000026297	RNASET2	69	54.000	ENSPLAG00000021835	-	81	54.194	Poecilia_latipinna
ENSG00000026297	RNASET2	97	49.296	ENSPLAG00000008033	-	86	49.541	Poecilia_latipinna
ENSG00000026297	RNASET2	87	34.211	ENSPMEG00000015109	-	83	34.211	Poecilia_mexicana
ENSG00000026297	RNASET2	97	48.826	ENSPMEG00000003615	-	86	49.083	Poecilia_mexicana
ENSG00000026297	RNASET2	97	48.826	ENSPMEG00000010682	-	86	49.083	Poecilia_mexicana
ENSG00000026297	RNASET2	75	41.818	ENSPREG00000014091	rnaset2	89	41.818	Poecilia_reticulata
ENSG00000026297	RNASET2	75	35.714	ENSPREG00000006683	rnaset2l	78	31.839	Poecilia_reticulata
ENSG00000026297	RNASET2	100	98.165	ENSPPYG00000017277	RNASET2	100	98.047	Pongo_abelii
ENSG00000026297	RNASET2	100	83.945	ENSPCOG00000019496	-	90	84.444	Propithecus_coquereli
ENSG00000026297	RNASET2	99	70.046	ENSPVAG00000003118	-	89	69.869	Pteropus_vampyrus
ENSG00000026297	RNASET2	54	37.190	ENSPNYG00000009261	rnaset2l	56	37.226	Pundamilia_nyererei
ENSG00000026297	RNASET2	87	35.294	ENSPNYG00000017856	rnaset2	94	35.111	Pundamilia_nyererei
ENSG00000026297	RNASET2	83	48.066	ENSPNAG00000006368	rnaset2	56	47.917	Pygocentrus_nattereri
ENSG00000026297	RNASET2	77	33.333	ENSPNAG00000010950	rnaset2l	77	33.520	Pygocentrus_nattereri
ENSG00000026297	RNASET2	98	71.028	ENSRNOG00000013190	Rnaset2	86	71.300	Rattus_norvegicus
ENSG00000026297	RNASET2	96	97.059	ENSRBIG00000038414	RNASET2	94	94.378	Rhinopithecus_bieti
ENSG00000026297	RNASET2	100	97.233	ENSRROG00000034809	RNASET2	100	96.875	Rhinopithecus_roxellana
ENSG00000026297	RNASET2	100	84.980	ENSSBOG00000022586	-	100	84.766	Saimiri_boliviensis_boliviensis
ENSG00000026297	RNASET2	95	66.827	ENSSHAG00000011073	-	84	66.972	Sarcophilus_harrisii
ENSG00000026297	RNASET2	97	46.262	ENSSFOG00015014347	rnaset2	88	46.847	Scleropages_formosus
ENSG00000026297	RNASET2	96	35.648	ENSSFOG00015005960	rnaset2l	86	35.043	Scleropages_formosus
ENSG00000026297	RNASET2	75	36.095	ENSSMAG00000004676	rnaset2l	63	35.754	Scophthalmus_maximus
ENSG00000026297	RNASET2	97	45.540	ENSSMAG00000003316	rnaset2	86	46.330	Scophthalmus_maximus
ENSG00000026297	RNASET2	97	43.662	ENSSDUG00000020833	rnaset2	97	42.714	Seriola_dumerili
ENSG00000026297	RNASET2	97	43.662	ENSSLDG00000025660	rnaset2	89	44.545	Seriola_lalandi_dorsalis
ENSG00000026297	RNASET2	75	33.333	ENSSPUG00000011766	-	71	32.759	Sphenodon_punctatus
ENSG00000026297	RNASET2	100	44.545	ENSSPAG00000019548	rnaset2	90	45.374	Stegastes_partitus
ENSG00000026297	RNASET2	75	35.714	ENSSPAG00000010405	rnaset2l	64	35.028	Stegastes_partitus
ENSG00000026297	RNASET2	100	68.037	ENSSSCG00000004024	-	100	68.037	Sus_scrofa
ENSG00000026297	RNASET2	97	57.547	ENSTGUG00000009538	-	98	58.065	Taeniopygia_guttata
ENSG00000026297	RNASET2	73	46.914	ENSTRUG00000001057	rnaset2	81	46.914	Takifugu_rubripes
ENSG00000026297	RNASET2	56	33.858	ENSTRUG00000022704	rnaset2l	60	33.835	Takifugu_rubripes
ENSG00000026297	RNASET2	56	35.433	ENSTNIG00000001634	rnaset2l	68	35.338	Tetraodon_nigroviridis
ENSG00000026297	RNASET2	97	43.318	ENSTNIG00000013801	rnaset2	89	44.196	Tetraodon_nigroviridis
ENSG00000026297	RNASET2	100	67.123	ENSTTRG00000004463	-	89	67.544	Tursiops_truncatus
ENSG00000026297	RNASET2	100	72.936	ENSUAMG00000009485	-	100	71.595	Ursus_americanus
ENSG00000026297	RNASET2	100	72.477	ENSUMAG00000011501	-	100	71.206	Ursus_maritimus
ENSG00000026297	RNASET2	98	71.163	ENSVVUG00000021691	-	93	74.107	Vulpes_vulpes
ENSG00000026297	RNASET2	99	52.778	ENSXETG00000016219	rnaset2	88	53.982	Xenopus_tropicalis
ENSG00000026297	RNASET2	97	48.357	ENSXMAG00000022893	rnaset2	88	49.083	Xiphophorus_maculatus
ENSG00000026297	RNASET2	75	35.714	ENSXMAG00000028432	rnaset2l	52	33.880	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	-	IEA	Function
GO:0004521	endoribonuclease activity	21873635.	IBA	Function
GO:0004540	ribonuclease activity	22735700.	IDA	Function
GO:0005576	extracellular region	21873635.	IBA	Component
GO:0005576	extracellular region	-	TAS	Component
GO:0005615	extracellular space	16502470.	HDA	Component
GO:0005615	extracellular space	16620762.	IDA	Component
GO:0005764	lysosome	16620762.	IDA	Component
GO:0005788	endoplasmic reticulum lumen	16620762.	IDA	Component
GO:0006401	RNA catabolic process	21873635.	IBA	Process
GO:0006401	RNA catabolic process	22735700.	IDA	Process
GO:0033897	ribonuclease T2 activity	-	IEA	Function
GO:0035578	azurophil granule lumen	-	TAS	Component
GO:0043202	lysosomal lumen	-	IEA	Component
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:0070062	extracellular exosome	23533145.	HDA	Component
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	-	IEA	Process

EuRBPDB

Note: to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Description

RBDs

Expression

Transcripts

Gene Model

Phenotype

GWAS

PPI

Ortholog

Gene Ontology

Note: Click here to get the extension of tumor abbreviations.

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742

Note: to get the extension of tumor abbreviations.