This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1)  human tyrosyl-tRNA synthetase  and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases . In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme . This domain may perform a common function in tRNA aminoacylation .
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
Simos G, Segref A, Fasiolo F, Hellmuth K, Shevchenko A, Mann M, Hurt EC; , EMBO J 1996;15:5437-5448.: The yeast protein Arc1p binds to tRNA and functions as a cofactor for the methionyl-and glutamyl-tRNA synthetases. PUBMED:8895587 EPMC:8895587.