Caenorhabditis_elegansFamily: rRNA_proc-arch Number of Genes: 2
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
skih-2
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mtr-4
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Introduction

Pfam

Mtr4 is the essential RNA helicase, and is an exosome-activating cofactor. This arch domain is carried in Mtr4 and Ski2 (the cytosolic homologue of Mtr4). The arch domain is required for proper 5.8S rRNA processing, and appears to function independently of canonical helicase activity [1].

InterPro

The essential RNA helicase Mtr4 is an exosome-activating cofactor. This arch domain can be found in Mtr4 and Ski2 (the cytosolic homologue of Mtr4). The arch domain is required for proper 5.8S rRNA processing, and appears to function independently of canonical helicase activity [PUBMED:20512111].

Reference

  1. Jackson RN, Klauer AA, Hintze BJ, Robinson H, van Hoof A, Johnson SJ;, EMBO J. 2010;29:2205-2216.: The crystal structure of Mtr4 reveals a novel arch domain required for rRNA processing. PUBMED:20512111 EPMC:20512111.