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Utp8 is an essential component of the nuclear tRNA export machinery in Saccharomyces cerevisiae. It is a tRNA binding protein that acts at a step between tRNA maturation /aminoacylation, and translocation of the tRNA across the nuclear pore complex .
Utp8 is an essential component of the nuclear tRNA export machinery in Saccharomyces cerevisiae. It is a tRNA binding protein that acts at a step between tRNA maturation/aminoacylation, and translocation of the tRNA across the nuclear pore complex [PUBMED:17634288]. It is also co-purified with the U3 snoRNA containing complex, the small subunit (SSU) processome, which is required for the biogenesis of the 18S rRNA [PUBMED:12068309].
Strub BR, Eswara MB, Pierce JB, Mangroo D; , Mol Biol Cell. 2007;18:3845-3859.: Utp8p Is a Nucleolar tRNA-binding Protein That Forms a Complex with Components of the Nuclear tRNA Export Machinery in Saccharomyces cerevisiae. PUBMED:17634288 EPMC:17634288 .
Dragon F, Gallagher JE, Compagnone-Post PA, Mitchell BM, Porwancher KA, Wehner KA, Wormsley S, Settlage RE, Shabanowitz J, Osheim Y, Beyer AL, Hunt DF, Baserga SJ; , Nature 2002;0:0-0.: A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. PUBMED:12068309 EPMC:12068309 .
Steiner-Mosonyi M, Leslie DM, Dehghani H, Aitchison JD, Mangroo D; , J Biol Chem. 2003;278:32236-32245.: Utp8p is an essential intranuclear component of the nuclear tRNA export machinery of Saccharomyces cerevisiae. PUBMED:12794079 EPMC:12794079.