Caenorhabditis_elegansFamily: Nop53 Number of Genes: 1
Ensembl IDSymbolEntrez IDRBD RBPome PRIExpresion PathwayPhenotype ParalogOrthologGO
Y39B6A.33
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Introduction

Pfam

This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation [3]. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60) [1]. This protein has been found to interact with herpes simplex type 1 regulatory proteins [1].

InterPro

No InterPro abstract

Reference

  1. Smith JS, Tachibana I, Pohl U, Lee HK, Thanarajasingam U, Portier BP, Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN, Jenkins RB; , Genomics 2000;64:44-50.: A transcript map of the chromosome 19q-arm glioma tumor suppressor region. PUBMED:10708517 EPMC:10708517 .

  2. Bruni R, Fineschi B, Ogle WO, Roizman B; , J Virol 1999;73:3810-3817.: A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infection. PUBMED:10196275 EPMC:10196275 .

  3. Sydorskyy Y, Dilworth DJ, Halloran BP, Yi EC, Makhnevych TR, Wozniak RW, Aitchison JD; , Biochem J 2005; [Epub ahead of print]: Nop53p is a novel nucleolar 60S ribosomal biogenesis protein. PUBMED:15686447 EPMC:15686447.